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Showing 1–4 of 4 results
Advanced filters: Author: Elizabeth Voke Clear advanced filters

  • The protein corona formed on nanoparticles can impact bioactivity. Here the authors show that the protein corona on lipid nanoparticles alters their function and reduces transfection efficiency, showing the importance of considering the protein corona in designing lipid nanoparticle-based therapeutics.

    • Elizabeth Voke
    • Mariah L. Arral
    • Markita P. Landry
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • Protein corona is crucial for the safety and efficacy of nanomedicines, and the protein composition of the corona layer is typically analysed using liquid chromatography-mass spectrometry. Here the authors report that the use of a uniform database search provides an opportunity for taking measures in good practice and quality control in protein corona research using mass spectroscopy technique.

    • Hassan Gharibi
    • Ali Akbar Ashkarran
    • Morteza Mahmoudi
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-9

  • Analysis of the protein corona formed around nanoparticles is important for multiple applications in nanomedicine, the methods used at core facilities used for analysis can impact the results. Here, the authors report on a study into the variability of the results obtained from 17 different core facilities and the implications of this.

    • Ali Akbar Ashkarran
    • Hassan Gharibi
    • Morteza Mahmoudi
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11

  • Current methods for the genetic manipulation of plants have low throughput and are amenable to a limited range of species. This Review discusses advances in the development of nanotechnology tools and the understanding of structure–function relationships to overcome these issues.

    • Henry J. Squire
    • Sophia Tomatz
    • Markita Landry
    Reviews
    Nature Reviews Bioengineering
    Volume: 1, P: 314-328