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Showing 1–8 of 8 results

Advanced filters: Author: Ellen Knuepfer Clear advanced filters

DNA-binding protein PfAP2-P regulates parasite pathogenesis during malaria parasite blood stages

The Plasmodium falciparum transcription factor PfAP2-P is an upstream regulator of parasite blood-stage development and regulates trophozoite development, host cell remodelling, antigenic variation and pathogenicity.

Amit Kumar Subudhi
Judith L. Green
Arnab Pain
ResearchOpen Access26 Oct 2023
Nature Microbiology

Volume: 8, P: 2154-2169
Generating conditional gene knockouts in Plasmodium – a toolkit to produce stable DiCre recombinase-expressing parasite lines using CRISPR/Cas9

Ellen Knuepfer
Marta Napiorkowska
Anthony A. Holder
ResearchOpen Access20 Jun 2017
Scientific Reports

Volume: 7, P: 1-12
The PfRCR complex bridges malaria parasite and erythrocyte during invasion

Structural studies show how the PfRCR complex of Plasmodium falciparum forms a bridge between erythrocyte and parasite membranes, and how PfCyRPA-binding antibodies neutralize invasion through a steric mechanism, opening the way to new approaches in rational vaccine design.

Brendan Farrell
Nawsad Alam
Matthew K. Higgins
ResearchOpen Access20 Dec 2023
Nature

Volume: 625, P: 578-584
Sequential roles for red blood cell binding proteins enable phased commitment to invasion for malaria parasites

Malaria parasites invade erythrocytes to proliferate, but visualizing this rapid process is challenging. Here the authors use live imaging and genome-editing of P. knowlesi to dissect invasion and establish the roles of two vital parasite proteins.

Melissa N. Hart
Franziska Mohring
Robert W. Moon
ResearchOpen Access01 Aug 2023
Nature Communications

Volume: 14, P: 1-15
Author Correction: Scalable and robust SARS-CoV-2 testing in an academic center

Jim Aitken
Karen Ambrose
Rachel Zillwood
Amendments and Corrections17 Jul 2020
Nature Biotechnology

Volume: 38, P: 1000
Deletion of Plasmodium falciparum ubc13 increases parasite sensitivity to the mutagen, methyl methanesulfonate and dihydroartemisinin

Supawadee Maneekesorn
Ellen Knuepfer
Anthony A. Holder
ResearchOpen Access08 Nov 2021
Scientific Reports

Volume: 11, P: 1-11
Genetic disruption of Plasmodium falciparum Merozoite surface antigen 180 (PfMSA180) suggests an essential role during parasite egress from erythrocytes

Vanndita Bahl
Kritika Chaddha
Deepak Gaur
ResearchOpen Access28 Sept 2021
Scientific Reports

Volume: 11, P: 1-13
Scalable and robust SARS-CoV-2 testing in an academic center

Jim Aitken
Karen Ambrose
Rachel Zillwood
Correspondence18 Jun 2020
Nature Biotechnology

Volume: 38, P: 927-931