Experiments show that charge heterogeneity in proteins affects their liquid-liquid phase separation (LLPS). Using a theoretically grounded and numerically efficient coarse-grained model, the authors study how the amount of charge and its surface distribution affects the LLPS. They find that electrostatics controls the connectivity of particles thus impacting the emergence of the LLPS.
- Daniele Notarmuzi
- Emanuela Bianchi
