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Showing 1–3 of 3 results
Advanced filters: Author: Emil G. P. Stender Clear advanced filters
  • Mycobacterium tuberculosis protein Ku is involved in DNA repair and a potential drug target. Here, using cryo-EM and complementary approaches, the authors obtain insights into Ku oligomerization and mechanisms of function in DNA synapsis.

    • Sayma Zahid
    • Sonia Baconnais
    • Amanda K. Chaplin
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13
  • Methods to quantitatively study liquid-liquid phase separation (LLPS) of proteins are lacking. Here the authors report Capillary flow experiments (Capflex) for the quantification of key LLPS parameters; they study Ddx4, the RP3 peptide and the aberrant liquid-to-solid phase transition of α-synuclein.

    • Emil G. P. Stender
    • Soumik Ray
    • Alexander K. Buell
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-18