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Showing 1–5 of 5 results
Advanced filters: Author: Emily Montal Clear advanced filters

  • Mechanical confinement of cancer cells at the tumour–microenvironment interface induces phenotype switching through chromatin remodelling by HMGB2, leading to a more invasive and drug-resistant state in melanoma.

    • Miranda V. Hunter
    • Eshita Joshi
    • Richard M. White
    ResearchOpen Access
    Nature
    Volume: 647, P: 517-527

  • Lipid droplets are a dynamic organelle found in a variety of cell types, most prominently in adipocytes. Here, the authors find in zebrafish and human cells that lipid droplets are enriched in a subset of melanoma cells that promote cancer formation and growth.

    • Dianne Lumaquin-Yin
    • Emily Montal
    • Richard M. White
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16

  • In a zebrafish model of human cutaneous and acral melanomas, CRKL amplification causes tumours to favour a fin location, indicating that tumour location is determined by both the driver oncogenes and the pre-existing positional identity gene program.

    • Joshua M. Weiss
    • Miranda V. Hunter
    • Richard M. White
    Research
    Nature
    Volume: 604, P: 354-361