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Showing 101–150 of 166 results

Advanced filters: Author: Emma L. Morgan Clear advanced filters

Role of Engrailed-2 (EN2) as a prostate cancer detection biomarker in genetically high risk men

Emma Killick
Richard Morgan
Hardev Pandha
ResearchOpen Access24 Jun 2013
Scientific Reports

Volume: 3, P: 1-5
Identification of genetic elements in metabolism by high-throughput mouse phenotyping

The genetic basis of metabolic diseases is incompletely understood. Here, by high-throughput phenotyping of 2,016 knockout mouse strains, Rozman and colleagues identify candidate metabolic genes, many of which are associated with unexplored regulatory gene networks and metabolic traits in human GWAS.

Jan Rozman
Birgit Rathkolb
Martin Hrabe de Angelis
ResearchOpen Access18 Jan 2018
Nature Communications

Volume: 9, P: 1-16
Separate lifetime signatures of macaque S cones, M/L cones, and rods observed with adaptive optics fluorescence lifetime ophthalmoscopy

Khang T. Huynh
Sarah Walters
Jennifer J. Hunter
ResearchOpen Access11 Feb 2023
Scientific Reports

Volume: 13, P: 1-12
Author Correction: Leaf nutrients, not specific leaf area, are consistent indicators of elevated nutrient inputs

Jennifer Firn
James M. McGree
Anita C. Risch
Amendments and Corrections15 May 2020
Nature Ecology & Evolution

Volume: 4, P: 886-891
Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals

Hayley H. A. Thorpe
Pierre Fontanillas
Sandra Sanchez-Roige
Research13 Oct 2025
Molecular Psychiatry

Volume: 31, P: 1061-1073
Active cdk6 complexes are predominantly nuclear and represent only a minority of the cdk6 in T cells

Daniel Mahony
David A Parry
Emma Lees
Research16 Feb 1998
Oncogene

Volume: 16, P: 603-611
Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Brian W. Kunkle
Benjamin Grenier-Boley
Margaret A. Pericak-Vance
Amendments and Corrections15 Aug 2019
Nature Genetics

Volume: 51, P: 1423-1424
Four consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards

Maja Kopczynska
Harry Unwin
Judith E. Hall
ResearchOpen Access10 Aug 2021
Scientific Reports

Volume: 11, P: 1-12
Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning

Sema Nickbakhsh
Joseph Hughes
Alison Smith-Palmer
ResearchOpen Access19 Jul 2022
Scientific Reports

Volume: 12, P: 1-17
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

Over one hundred loci have been identified to be associated with the familial risk of prostate cancer but the functional effects are poorly understood. Here the authors use single-nucleotide variant and epigentic data to show an underlying genetic architecture marked by histone modification.

Alexander Gusev
Huwenbo Shi
Bogdan Pasaniuc
ResearchOpen Access07 Apr 2016
Nature Communications

Volume: 7, P: 1-13
E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer

Molly R. Patterson
Aniek S. Meijers
Andrew Macdonald
ResearchOpen Access24 May 2024
Oncogene

Volume: 43, P: 2184-2198
Chimpanzee accumulative stone throwing

Hjalmar S. Kühl
Ammie K. Kalan
Christophe Boesch
ResearchOpen Access29 Feb 2016
Scientific Reports

Volume: 6, P: 1-8
Therapeutic modulation of Notch signalling — are we there yet?

The Notch signalling pathway, which is crucial for the development and homeostasis of most tissues, has been linked to a range of diseases, including cancer. Andersson and Lendahl discuss where and how to intervene therapeutically in the Notch signalling pathway, highlighting current achievements and remaining obstacles.

Emma R. Andersson
Urban Lendahl
Reviews30 Apr 2014
Nature Reviews Drug Discovery

Volume: 13, P: 357-378
Publisher Correction: Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer

Kroopa Joshi
Marc Robert de Massy
Benny Chain
Amendments and Corrections03 Jun 2020
Nature Medicine

Volume: 26, P: 1148
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

Copy number variants (CNVs) account for a major proportion of human genetic diversity and may contribute to genetic susceptibility to disease. Here, a large, genome-wide study of association between common CNVs and eight common human diseases is presented. The study provides a wealth of technical insights that will inform future study design and analysis. The results also indicate that common CNVs that can be 'typed' on existing platforms are unlikely to contribute much to the genetic basis of common diseases.

Nick Craddock
Matthew E. Hurles
Peter Donnelly
Research01 Apr 2010
Nature

Volume: 464, P: 713-720
Miscarriage and stillbirth following maternal Zika virus infection in nonhuman primates

Zika virus infection during pregnancy is associated with an increased rate of fetal loss in nonhuman primates, as reported in this multicenter analysis.

Dawn M. Dudley
Koen K. Van Rompay
David H. O’Connor
Research02 Jul 2018
Nature Medicine

Volume: 24, P: 1104-1107
Methylomic signature of current cannabis use in two first-episode psychosis cohorts

Emma L. Dempster
Chloe C. Y. Wong
Marta Di Forti
ResearchOpen Access16 Oct 2024
Molecular Psychiatry

Volume: 30, P: 1277-1286
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

Rosalind Eeles and colleagues report meta-analysis of genome-wide association studies for prostate cancer and genotyping on the custom iCOGS array in 25,074 cases and 24,272 controls from 32 studies available in the PRACTICAL Consortium. They identify 23 new prostate cancer susceptibility loci, 20 of which are associated with both aggressive and non-aggressive disease.

Rosalind A Eeles
Ali Amin Al Olama
Douglas F Easton
Research27 Mar 2013
Nature Genetics

Volume: 45, P: 385-391
Author Correction: Modeling COVID-19 scenarios for the United States

Robert C. Reiner Jr
Ryan M. Barber
Christopher J. L. Murray
Amendments and CorrectionsOpen Access27 Nov 2020
Nature Medicine

Volume: 26, P: 1950
Publisher Correction: Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse

Francesca Chemi
Dominic G. Rothwell
Jason Lester
Amendments and Corrections03 Jun 2020
Nature Medicine

Volume: 26, P: 1147
A clonal expression biomarker associates with lung cancer mortality

TRACERx Lung: Intratumoral transcriptional heterogeneity, which often hinders the development of clinically useful RNA-expression-biased biomarkers for cancer, can now be overcome with an approach for the identification of clonal expression biomarkers.

Dhruva Biswas
Nicolai J. Birkbak
Angeles Montero
Research07 Oct 2019
Nature Medicine

Volume: 25, P: 1540-1548
Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease

Whole-exome sequencing reveals that a rare variant of phospholipase D3 (PLD3(V232M)) segregates with Alzheimer’s disease status in two independent families and doubles risk for the disease in case–control series, and that several other PLD3 variants increase risk for Alzheimer’s disease in African Americans and people of European descent.

Carlos Cruchaga
Celeste M. Karch
Alison M. Goate
Research11 Dec 2013
Nature

Volume: 505, P: 550-554
Publisher Correction: A clonal expression biomarker associates with lung cancer mortality

Dhruva Biswas
Nicolai J. Birkbak
Angeles Montero
Amendments and Corrections03 Jun 2020
Nature Medicine

Volume: 26, P: 1148
Protein–ligand data at scale to support machine learning

Target 2035 aims to develop a potent and selective pharmacological modulator for every human protein by 2035 with the results made publicly available. This Roadmap article sets out how that will be achieved.

Aled M. Edwards
Dafydd R. Owen
Suzanne Ackloo
Reviews23 Jul 2025
Nature Reviews Chemistry

Volume: 9, P: 634-645
Author Correction: Discovery of a radiation component from the Vela pulsar reaching 20 teraelectronvolts

F. Aharonian
F. Ait Benkhali
D. A. Smith
Amendments and Corrections06 Nov 2023
Nature Astronomy

Volume: 8, P: 145
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma

Multiregion spatial histology, exome and transcriptome data from patients with non-small cell lung cancer suggest that cancer subclones from immune cold regions diversify later than subclones from immune hot regions

Khalid AbdulJabbar
Shan E. Ahmed Raza
Yinyin Yuan
Research27 May 2020
Nature Medicine

Volume: 26, P: 1054-1062
The T cell differentiation landscape is shaped by tumour mutations in lung cancer

Ghorani et al. use a multiomics approach to characterize the effect of tumour mutational burden on the differentiation of CD4 and CD8 T cell subpopulations in non-small cell lung cancer.

Ehsan Ghorani
James L. Reading
Sergio A. Quezada
Research22 May 2020
Nature Cancer

Volume: 1, P: 546-561
Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse

Pulmonary venous tumor cells disseminating before tumor resection are heterogeneous, predict relapse and seed future metastasis of lung cancer

Francesca Chemi
Dominic G. Rothwell
Jason Lester
Research07 Oct 2019
Nature Medicine

Volume: 25, P: 1534-1539
The impact of immediate breast reconstruction on the time to delivery of adjuvant therapy: the iBRA-2 study

Rachel L O’Connell
Tim Rattay
Mohammed Mustafa
ResearchOpen Access29 Mar 2019
British Journal of Cancer

Volume: 120, P: 883-895
Precise identification of cell states altered in disease using healthy single-cell references

In single-cell studies, combining healthy reference atlases and designed control datasets allows more precise identification of disease-associated cell states.

Emma Dann
Ana-Maria Cujba
John C. Marioni
ResearchOpen Access12 Oct 2023
Nature Genetics

Volume: 55, P: 1998-2008
Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)

The Human BioMolecular Atlas Program (HuBMAP) presents its production phase: the generation of spatial maps of functional tissue units across organs from diverse populations and the creation of tools and infrastructure to advance biomedical research.

Sanjay Jain
Liming Pei
Michael P. Snyder
Reviews19 Jul 2023
Nature Cell Biology

Volume: 25, P: 1089-1100
Exploratory digital outcome measures of motor sign progression in Parkinson’s disease patients treated with prasinezumab

Kirsten I. Taylor
Florian Lipsmeier
Stefano Zanigni
ResearchOpen Access16 Jun 2025
npj Digital Medicine

Volume: 8, P: 1-12
WAND: A multi-modal dataset integrating advanced MRI, MEG, and TMS for multi-scale brain analysis

Carolyn B. McNabb
Ian D. Driver
Derek K. Jones
ResearchOpen Access06 Feb 2025
Scientific Data

Volume: 12, P: 1-19
Author Correction: Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)

Sanjay Jain
Liming Pei
Michael P. Snyder
Amendments and Corrections01 Mar 2024
Nature Cell Biology

Volume: 26, P: 839
VinCaP: a phase II trial of vinflunine in locally advanced and metastatic squamous carcinoma of the penis

Steve Nicholson
Holly Tovey
Lisa M. Pickering
ResearchOpen Access20 Oct 2021
British Journal of Cancer

Volume: 126, P: 34-41
Reprograming of gut microbiome energy metabolism by the FUT2 Crohn’s disease risk polymorphism

Maomeng Tong
Ian McHardy
Jonathan Braun
ResearchOpen Access29 Apr 2014
The ISME Journal

Volume: 8, P: 2193-2206
Recent genetic connectivity and clinal variation in chimpanzees

Lester and colleagues use faecal samples and genetic analyses to investigate the genetic connectivity across chimpanzees. Their results indicate that the global pattern of genetic diversity in chimpanzees is largely characterized by a pattern of isolation by distance with several isolated populations exhibiting strong local differentiation.

Jack D. Lester
Linda Vigilant
Mimi Arandjelovic
ResearchOpen Access05 Mar 2021
Communications Biology

Volume: 4, P: 1-11
Exploring the mediation of DNA methylation across the epigenome between childhood adversity and First Episode of Psychosis—findings from the EU-GEI study

Luis Alameda
Zhonghua Liu
Chloe C. Y. Wong
Research17 Apr 2023
Molecular Psychiatry

Volume: 28, P: 2095-2106
Physical and transcriptional map of the critical region for keratolytic winter erythema (KWE) on chromosome 8p22-p23 between D8S550 and D8S1759

Silke Appel
Matthias Filter
André Rosenthal
Research28 Feb 2002
European Journal of Human Genetics

Volume: 10, P: 17-25
Genetic aetiologies for childhood speech disorder: novel pathways co-expressed during brain development

Antony Kaspi
Michael S. Hildebrand
Angela T. Morgan
ResearchOpen Access18 Sept 2022
Molecular Psychiatry

Volume: 28, P: 1647-1663
Author Correction: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

Itziar de Rojas
Sonia Moreno-Grau
Agustín Ruiz
Amendments and CorrectionsOpen Access09 Feb 2023
Nature Communications

Volume: 14, P: 1-2
Correction: WAND: A multi-modal dataset integrating advanced MRI, MEG, and TMS for multi-scale brain analysis

Carolyn B. McNabb
Ian D. Driver
Derek K. Jones
Amendments and CorrectionsOpen Access03 Jul 2025
Scientific Data

Volume: 12, P: 1
Abuse liability—study the intended patient populations

Alec B. O'Connor
Dennis C. Turk
Robert H. Dworkin
Correspondence10 Feb 2015
Nature Reviews Neurology

Volume: 11, P: 182
Investigation of relationship between vitamin D status and reproductive fitness in Scottish hill sheep

Ping Zhou
Thomas G. McEvoy
Richard J. Mellanby
ResearchOpen Access04 Feb 2019
Scientific Reports

Volume: 9, P: 1-10
Biofilms harbour Clostridioides difficile, serving as a reservoir for recurrent infection

Charmaine Normington
Ines B. Moura
Anthony M. Buckley
ResearchOpen Access05 Feb 2021
npj Biofilms and Microbiomes

Volume: 7, P: 1-10
Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer

Rebecca J. van Kalsbeek
Melissa M. Hudson
Lisa Zwiers
Amendments and Corrections22 May 2024
Nature Medicine

Volume: 30, P: 2091
The impact of ethnicity on asthma care

Emma Davidson
Jing Jing Liu
Aziz Sheikh
Reviews27 Apr 2010
Primary Care Respiratory Journal

Volume: 19, P: 202-208
A joint international consensus statement for measuring quality of survival for patients with childhood cancer

The International Childhood Cancer Outcome Project group, involving survivors and other relevant stakeholders, develop a set of core outcomes to measure the quality of care for 17 types of childhood cancers.

Rebecca J. van Kalsbeek
Melissa M. Hudson
Lisa Zwiers
Reviews15 Jun 2023
Nature Medicine

Volume: 29, P: 1340-1348
A global assemblage of regional prescribed burn records — GlobalRx

Alice Hsu
Matthew W. Jones
Emma Zerr
ResearchOpen Access01 Jul 2025
Scientific Data

Volume: 12, P: 1-30
A novel Alzheimer disease locus located near the gene encoding tau protein

G Jun
C A Ibrahim-Verbaas
L A Farrer
Research17 Mar 2015
Molecular Psychiatry

Volume: 21, P: 108-117

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