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Showing 1–6 of 6 results
Advanced filters: Author: Emmanuel Caussinus Clear advanced filters

  • Asymmetric cell division can generate daughter cells with cell size asymmetry, but the underlying mechanisms are not clear. Here the authors show that spatiotemporally controlled Myosin flows together with spindle asymmetry and positioning control cleavage furrow position and cortical expansion to establish physical asymmetry.

    • Chantal Roubinet
    • Anna Tsankova
    • Clemens Cabernard
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-16

  • The morphogen Decapentaplegic (Dpp) has been implicated in both wing patterning and growth in fruitflies; here, a nanobody-based morphotrap approach has been developed that rules out a role for the Dpp gradient in regulating lateral wing growth.

    • Stefan Harmansa
    • Fisun Hamaratoglu
    • Emmanuel Caussinus
    Research
    Nature
    Volume: 527, P: 317-322

  • The combination of an F-box domain with a single-domain antibody that recognizes green fluorescent protein (GFP) now allows controlled depletion of GFP fusions in mammalian cells and in flies. This system, called deGradFP, should be widely useful, as GFP fusions are available for many proteins in model organisms.

    • Emmanuel Caussinus
    • Oguz Kanca
    • Markus Affolter
    Research
    Nature Structural & Molecular Biology
    Volume: 19, P: 117-121

  • Branched structures are present at all levels of organization in living organisms. Recent studies suggest that cell competition and cell rearrangements might be conserved key features in branch formation that are controlled by local cell signalling events.

    • Markus Affolter
    • Rolf Zeller
    • Emmanuel Caussinus
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 10, P: 831-842