Understanding how and where HIV-1 infection persists in the body is crucial for efforts to eradicate the viral reservoir. Now Mathias Lichterfeld and his colleagues report that HIV-1 can infect CD4+ T memory stem cells (TSCM cells) and that infected TSCM cells constitute a stable component of the viral reservoir in individuals treated with antiretroviral therapy.
- Maria J Buzon
- Hong Sun
- Mathias Lichterfeld