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Erratum: TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export

Nicolas Viphakone
Guillaume M. Hautbergue
Stuart A. Wilson
Amendments and Corrections17 Oct 2013
Nature Communications

Volume: 4, P: 1-3
Mammalian PERIOD2 regulates H2A.Z incorporation in chromatin to orchestrate circadian negative feedback

Circadian clocks both instruct and follow the epigenome. New data reveal that the core-clock PERIOD complex shapes genomic H2A.Z landscapes. H2A.Z, in turn, plays an essential role in rhythm generation by regulating BMAL1 stability.

Kevin Tartour
Francesca Andriani
Kiran Padmanabhan
Research23 May 2022
Nature Structural & Molecular Biology

Volume: 29, P: 549-562
TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export

The TREX complex and Nxf1 are involved in the export of mRNA from the nucleus but the precise molecular function of TREX is unclear. Here, the TREX components Aly and Thoc5 are shown to bind to Nxf1 resulting in a change in Nxf1 conformation that permits binding to mRNA and nuclear export.

Nicolas Viphakone
Guillaume M. Hautbergue
Stuart A. Wilson
Research14 Aug 2012
Nature Communications

Volume: 3, P: 1-14
H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers

The small molecule H3B-8800 selectively modulates RNA splicing to preferentially kill tumor cells bearing mutations in genes encoding spliceosome components.

Michael Seiler
Akihide Yoshimi
Silvia Buonamici
Research19 Feb 2018
Nature Medicine

Volume: 24, P: 497-504
Bromodomain factors of BET family are new essential actors of pericentric heterochromatin transcriptional activation in response to heat shock

Edwige Col
Neda Hoghoughi
Claire Vourc’h
ResearchOpen Access14 Jul 2017
Scientific Reports

Volume: 7, P: 1-12