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Showing 1–5 of 5 results

Advanced filters: Author: Eric Galburt Clear advanced filters

Oligomerisation of Ku from Mycobacterium tuberculosis promotes DNA synapsis

Mycobacterium tuberculosis protein Ku is involved in DNA repair and a potential drug target. Here, using cryo-EM and complementary approaches, the authors obtain insights into Ku oligomerization and mechanisms of function in DNA synapsis.

Sayma Zahid
Sonia Baconnais
Amanda K. Chaplin
ResearchOpen Access26 Nov 2025
Nature Communications

Volume: 16, P: 1-13
A novel endonuclease mechanism directly visualized for I-PpoI

Eric A. Galburt
Brett Chevalier
Barry L. Stoddard
Research01 Dec 1999
Nature Structural Biology

Volume: 6, P: 1096-1099
Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner

Eric A. Galburt
Stephan W. Grill
Carlos Bustamante
Research14 Mar 2007
Nature

Volume: 446, P: 820-823
TFIIH generates a six-base-pair open complex during RNAP II transcription initiation and start-site scanning

During transcription initiation, Ssl2, the dsDNA translocase of TFIIH, opens a 6-bp DNA bubble, suggesting a two-step model wherein Ssl2 triggers a 6-bp open complex that RNA polymerase II expands via NTP-dependent RNA transcription.

Eric J Tomko
James Fishburn
Eric A Galburt
Research06 Nov 2017
Nature Structural & Molecular Biology

Volume: 24, P: 1139-1145
Restriction endonucleases: one of these things is not like the others

Eric A. Galburt
Barry L. Stoddard
News & Views01 Feb 2000
Nature Structural Biology

Volume: 7, P: 89-91