Nature Search

Retraction Note: Pericyte degeneration causes white matter dysfunction in the mouse central nervous system

Axel Montagne
Angeliki M. Nikolakopoulou
Berislav V. Zlokovic
Amendments and Corrections05 Apr 2024
Nature Medicine

Volume: 30, P: 1215
Vascular heterogeneity of tight junction Claudins guides organotropic metastasis

Kalluri and colleagues use mammary carcinoma models to study the causes of metastatic organotropism and find an organ-specific role for angiopoietin 2 in driving lung metastasis through the suppression of the tight junction protein Claudin 5.

Xunian Zhou
Valerie S. LeBleu
Raghu Kalluri
Research17 Sept 2024
Nature Cancer

Volume: 5, P: 1371-1389
Mapping variants in thyroid hormone transporter MCT8 to disease severity by genomic, phenotypic, functional, structural and deep learning integration

Loss-of-function variants in thyroid hormone transporter MCT8 cause a neurodevelopmental and metabolic disorder. Here the authors identify genotype-phenotype relationships, advance insights in MCT8 (dys)function and create a pathogenicity-severity variant classifier.

Stefan Groeneweg
Ferdy S. van Geest
W. Edward Visser
ResearchOpen Access12 Mar 2025
Nature Communications

Volume: 16, P: 1-21
ZFP281 drives a mesenchymal-like dormancy program in early disseminated breast cancer cells that prevents metastatic outgrowth in the lung

Aguirre-Ghiso and colleagues report that the pluripotency transcription factor ZFP281 promotes dormancy of early disseminated breast cancer cells in the lung by driving a mesenchymal-like gene expression program.

Ana Rita Nobre
Erica Dalla
Julio A. Aguirre-Ghiso
Research01 Sept 2022
Nature Cancer

Volume: 3, P: 1165-1180
Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes

An integrated analysis of de novo and inherited coding variants in 42,607 individuals with autism spectrum disorder identifies 60 risk genes of which five have not previously been associated with neurodevelopmental disorders.

Xueya Zhou
Pamela Feliciano
Wendy K. Chung
ResearchOpen Access18 Aug 2022
Nature Genetics

Volume: 54, P: 1305-1319
Author Correction: APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer’s mice via cyclophilin A independently of amyloid-β

Axel Montagne
Angeliki M. Nikolakopoulou
Berislav V. Zlokovic
Amendments and Corrections29 Jun 2021
Nature Aging

Volume: 1, P: 624
APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer’s mice via cyclophilin A independently of amyloid-β

This study shows that APOE4, one of the largest genetic risk factors for Alzheimer’s disease, promotes advanced-stage vascular dysfunction and neurodegeneration in old mice via activation of the cyclophilin A pathway in pericytes and independently of the presence of amyloid-β.

Axel Montagne
Angeliki M. Nikolakopoulou
Berislav V. Zlokovic
Research14 Jun 2021
Nature Aging

Volume: 1, P: 506-520
Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss

Using pericyte-specific Cre and ablation mouse lines, the authors show that loss of brain pericytes leads to circulatory failure and reduced pleiotrophin causing rapid neuron loss. These findings link pericyte loss to a rapid neurodegeneration cascade.

Angeliki M. Nikolakopoulou
Axel Montagne
Berislav V. Zlokovic
Research24 Jun 2019
Nature Neuroscience

Volume: 22, P: 1089-1098
The physics of dissent and the effects of movement momentum

Chenoweth and Belgioioso describe the momentum of protest movements as the product of the number of participants (mass) and concentration of events in time (velocity). Higher momentum is associated with a higher probability of irregular leader exit.

Erica Chenoweth
Margherita Belgioioso
Research05 Aug 2019
Nature Human Behaviour

Volume: 3, P: 1088-1095
RETRACTED ARTICLE: Pericyte degeneration causes white matter dysfunction in the mouse central nervous system

Degeneration of pericytes causes toxic fibrin(ogen) accumulation, cell death and microcirculation dysfunction in CNS white-matter axon tracts.

Axel Montagne
Angeliki M Nikolakopoulou
Berislav V Zlokovic
Research05 Feb 2018
Nature Medicine

Volume: 24, P: 326-337
The Somatic Mosaicism across Human Tissues Network

The Somatic Mosaicism across Human Tissues Network aims to create a reference catalogue of somatic mosaicism across different tissues and cells within individuals.

Tim H. H. Coorens
Ji Won Oh
Yuqing Wang
Reviews02 Jul 2025
Nature

Volume: 643, P: 47-59
Tissue engineered vascular grafts transform into autologous neovessels capable of native function and growth

Blum et al. combine computational and experimental methods to study the long-term development of tissue engineered vascular grafts in a lamb model. The authors demonstrate that the grafts undergo growth and remodeling, evolving to mimic the characteristics and function of a native blood vessel.

Kevin M. Blum
Jacob C. Zbinden
Christopher K. Breuer
ResearchOpen Access10 Jan 2022
Communications Medicine

Volume: 2, P: 1-21

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Retraction Note: Pericyte degeneration causes white matter dysfunction in the mouse central nervous system

Vascular heterogeneity of tight junction Claudins guides organotropic metastasis

Mapping variants in thyroid hormone transporter MCT8 to disease severity by genomic, phenotypic, functional, structural and deep learning integration

ZFP281 drives a mesenchymal-like dormancy program in early disseminated breast cancer cells that prevents metastatic outgrowth in the lung

Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes

Author Correction: APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer’s mice via cyclophilin A independently of amyloid-β

APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer’s mice via cyclophilin A independently of amyloid-β

Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss

The physics of dissent and the effects of movement momentum

RETRACTED ARTICLE: Pericyte degeneration causes white matter dysfunction in the mouse central nervous system

The Somatic Mosaicism across Human Tissues Network

Tissue engineered vascular grafts transform into autologous neovessels capable of native function and growth

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