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Showing 1–15 of 15 results
Advanced filters: Author: Erich Bornberg-Bauer Clear advanced filters
  • De novo gene evolution entails the birth of new genes from previously non-coding DNA. In this Review, Bornberg-Bauer and Eicholt overview how protein-coding de novo genes are identified, the mechanistic and evolutionary processes underlying their emergence and evolution, and the patterns in their encoded protein structures.

    • Erich Bornberg-Bauer
    • Lars A. Eicholt
    Reviews
    Nature Reviews Genetics
    P: 1-17
  • Eusociality evolved independently in Hymenoptera and in termites. Here, the authors sequence genomes of the German cockroach and a drywood termite and provide insights into the evolutionary signatures of termite eusociality.

    • Mark C. Harrison
    • Evelien Jongepier
    • Erich Bornberg-Bauer
    ResearchOpen Access
    Nature Ecology & Evolution
    Volume: 2, P: 557-566
  • New protein coding genes can emerge de novo overlapping existing protein genes but in the opposite orientation. Here, the authors investigate the possibility of such events using mathematical modelling and data analysis, and find that emergence of a protein coding region is generally most likely in one frame of overlap (frame 1).

    • Bharat Ravi Iyengar
    • Anna Grandchamp
    • Erich Bornberg-Bauer
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-11
  • Reference assemblies of great ape sex chromosomes show that Y chromosomes are more variable in size and sequence than X chromosomes and provide a resource for studies on human evolution and conservation genetics of non-human apes.

    • Kateryna D. Makova
    • Brandon D. Pickett
    • Adam M. Phillippy
    ResearchOpen Access
    Nature
    Volume: 630, P: 401-411
  • While a bioinformatic comparison of de novo genes and synthetic random sequence does not identify a difference in biophysical properties, in vitro expression shows higher solubility for the de novo proteins, suggesting better integration into the cellular system than random sequences.

    • Brennen Heames
    • Filip Buchel
    • Klára Hlouchová
    ResearchOpen Access
    Nature Ecology & Evolution
    Volume: 7, P: 570-580
  • Growing evidence suggests that de novo genes originating from noncoding DNA are common. Here the authors show that while open reading frames pervasively emerge from noncoding sequences, most are lost; nevertheless a few can be translated and give rise to new protein-coding genes.

    • Jonathan F. Schmitz
    • Kristian K. Ullrich
    • Erich Bornberg-Bauer
    Research
    Nature Ecology & Evolution
    Volume: 2, P: 1626-1632
  • Previous work identified goddard as a putative de novo evolved gene in Drosophila melanogaster. Here, the authors characterize the structure and function of the Goddard protein in D. melanogaster, and they infer its ancestral and extant structures across the Drosophila genus.

    • Andreas Lange
    • Prajal H. Patel
    • Erich Bornberg-Bauer
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13
  • Ancestral protein reconstruction followed by biochemical and structural analyses characterizes the evolutionary trajectory of methyl-parathion hydrolase from an ancestral dihydrocoumarin hydrolase through the accumulation of five key mutations.

    • Gloria Yang
    • Dave W Anderson
    • Nobuhiko Tokuriki
    Research
    Nature Chemical Biology
    Volume: 15, P: 1120-1128
  • Although termites are major human pests, they have an important role in maintaining ecosystem function and biodiversity. Here, the authors sequence the genome and transcriptomes of a dampwood termite and highlight genes that may be involved in the mechanisms underlying insect social behaviour.

    • Nicolas Terrapon
    • Cai Li
    • Jürgen Liebig
    ResearchOpen Access
    Nature Communications
    Volume: 5, P: 1-12
  • Analysis of genomes, transcriptomes and proteomes from recently diverged rice species provides mechanistic insight into the process of de novo gene origination.

    • Erich Bornberg-Bauer
    • Brennen Heames
    News & Views
    Nature Ecology & Evolution
    Volume: 3, P: 524-525
  • The Eucalyptus grandis genome has been sequenced, revealing the greatest number of tandem duplications of any plant genome sequenced so far, and the highest diversity of genes for specialized metabolites that act as chemical defence and provide unique pharmaceutical oils; genome sequencing of the sister species E. globulus and a set of inbred E. grandis tree genomes reveals dynamic genome evolution and hotspots of inbreeding depression.

    • Alexander A. Myburg
    • Dario Grattapaglia
    • Jeremy Schmutz
    ResearchOpen Access
    Nature
    Volume: 510, P: 356-362
  • Whole-genome sequencing of the seagrass Zostera, representing the first marine angiosperm genome to be fully sequenced, provides insight into the evolutionary changes associated with a transition to a marine environment in this angiosperm lineage.

    • Jeanine L. Olsen
    • Pierre Rouzé
    • Yves Van de Peer
    ResearchOpen Access
    Nature
    Volume: 530, P: 331-335
  • Séité, Harrison, et al. investigate the mechanisms underlying long lifespan in queens and kings of the highly social termite Macrotermes natalensis. Using transcriptomics, lipidomics and metabolomics, this study shows that several aging-related processes are reduced in the fat bodies of these reproductives and that an upregulated insulin-like peptide, Ilp9, does not lead to deleterious fat storage in old queens, while simple sugars dominate in their hemolymph.

    • Sarah Séité
    • Mark C. Harrison
    • Mireille Vasseur-Cognet
    ResearchOpen Access
    Communications Biology
    Volume: 5, P: 1-16