The nasopharynx-associated lymphoid tissue (NALT) of terrestrial mammals serves as a first line of defence against pathogens. Here the authors show that fish also have NALT, characterized by the presence of diffuse lymphoid cells including IgT+B cells, and demonstrate successful intranasal immunization.
- Luca Tacchi
- Rami Musharrafieh
- Irene Salinas
