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Showing 1–6 of 6 results

Advanced filters: Author: Erik S. Welf Clear advanced filters

Real-time multi-angle projection imaging of biological dynamics

Multiangle projection imaging accelerates volumetric imaging by up to two orders of magnitude and is readily implemented on diverse microscopes, including spinning disk confocal and light-sheet microscopes.

Bo-Jui Chang
James D. Manton
Reto Fiolka
Research28 Jun 2021
Nature Methods

Volume: 18, P: 829-834
Blebs promote cell survival by assembling oncogenic signalling hubs

A study demonstrates that sustained membrane blebs in cancer cells recruit curvature-sensing septins that form plasma membrane-proximal signalling hubs that promote cancer cell survival.

Andrew D. Weems
Erik S. Welf
Gaudenz Danuser
Research01 Mar 2023
Nature

Volume: 615, P: 517-525
Robust and automated detection of subcellular morphological motifs in 3D microscopy images

A computational workflow combining image segmentation, computer graphics and supervised machine learning enables automated and robust 3D analysis of the coupling of cell shape and signaling.

Meghan K. Driscoll
Erik S. Welf
Gaudenz Danuser
Research09 Sept 2019
Nature Methods

Volume: 16, P: 1037-1044
A bright cyan-excitable orange fluorescent protein facilitates dual-emission microscopy and enhances bioluminescence imaging in vivo

In vivo imaging is facilitated by a bright, cyan-excitable orange fluorescent protein that is the basis of an improved bioluminescent protein.

Jun Chu
Younghee Oh
Michael Z Lin
Research30 May 2016
Nature Biotechnology

Volume: 34, P: 760-767
Nuclear positioning facilitates amoeboid migration along the path of least resistance

Geometrically defined microenvironments are used to show that leukocytes migrate along chemokine gradients using the nucleus as a mechanical gauge to sample potential paths and identify the path of least resistance.

Jörg Renkawitz
Aglaja Kopf
Michael Sixt
Research03 Apr 2019
Nature

Volume: 568, P: 546-550
Universal light-sheet generation with field synthesis

The field synthesis method for generating any scanned light sheet is based on a new mathematical theorem in Fourier analysis and has important practical implications for simpler, multicolor lattice light-sheet microscopy.

Bo-Jui Chang
Mark Kittisopikul
Reto Fiolka
Research25 Feb 2019
Nature Methods

Volume: 16, P: 235-238