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Nature Genetics (1)

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Long-range interactions between topologically associating domains shape the four-dimensional genome during differentiation

The authors identify the formation of dynamic topologically associating domain (TAD) cliques during differentiation and reprogramming. Their analysis indicates that TAD cliques stabilize heterochromatin at the nuclear periphery.

Jonas Paulsen
Tharvesh M. Liyakat Ali
Philippe Collas
Research22 Apr 2019
Nature Genetics

Volume: 51, P: 835-843

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Long-range interactions between topologically associating domains shape the four-dimensional genome during differentiation

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