An altered microglial landscape and ageing-related inflammatory changes contribute to the neurodegeneration associated with frontotemporal dementia (FTD). Here, Bright and colleagues discuss the evidence for a pathogenetic role of neuroinflammatory mechanisms in FTD, including links with autoimmunity and gene mutations associated with neuroinflammation.
- Fiona Bright
- Eryn L. Werry
- Jillian J. Kril
