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Showing 1–7 of 7 results
Advanced filters: Author: Esther Bui Clear advanced filters

  • National climate institutions could greatly impact the process of policy design and implementation. This analysis identifies four models of climate governance for major emitters, estimates their policy ambitions and performance, then shows how they are related to macro features.

    • Johnathan Guy
    • Esther Shears
    • Jonas Meckling
    Research
    Nature Climate Change
    Volume: 13, P: 189-195

  • Temporal lobe epilepsy in adults does not always respond to treatment. Krook-Magnuson and colleagues use optogenetics to inhibit and activate excitatory and inhibitory neurons, respectively, in a mouse model of temporal lobe epilepsy, and find that they can stop seizures on a moment-to-moment basis.

    • Esther Krook-Magnuson
    • Caren Armstrong
    • Ivan Soltesz
    ResearchOpen Access
    Nature Communications
    Volume: 4, P: 1-8

  • Douglas Easton and colleagues report a genome-wide association analyses for breast cancer in ~70,000 cases and ~68,000 controls. They identify three new breast cancer susceptibility loci, two of which show association only with estrogen receptor–positive disease.

    • Maya Ghoussaini
    • Olivia Fletcher
    • Douglas F Easton
    Research
    Nature Genetics
    Volume: 44, P: 312-318

  • A phase I dose-escalation trial of GD2-CAR T cells in children and young adults with diffuse midline gliomas to assess the feasibility of manufacturing, safety and tolerability, and to preliminarily assess efficacy.

    • Robbie G. Majzner
    • Sneha Ramakrishna
    • Michelle Monje
    ResearchOpen Access
    Nature
    Volume: 603, P: 934-941

  • Montserrat Garcia-Closas and colleagues report a meta-analysis of three genome-wide association studies for estrogen receptor (ER)-negative breast cancer, including 4,193 ER-negative breast cancer cases and 35,194 controls, with replication using the iCOGS custom genotyping array in 40 studies, including 6,514 cases and 41,455 controls. They identify four loci associated with ER-negative but not ER-positive breast cancer.

    • Montserrat Garcia-Closas
    • Fergus J Couch
    • Peter Kraft
    Research
    Nature Genetics
    Volume: 45, P: 392-398