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Neoadjuvant enoblituzumab in localized prostate cancer: a single-arm, phase 2 trial

In a single-arm phase 2 study, enoblituzumab (a humanized, Fc-engineered, B7-H3-targeting antibody) was found to be safe and showed preliminary evidence of potential clinical activity in men with high-risk localized prostate cancer.

Eugene Shenderov
Angelo M. De Marzo
Emmanuel S. Antonarakis
Research03 Apr 2023
Nature Medicine

Volume: 29, P: 888-897
Hypothermic machine perfusion prevents hyperacute graft loss in pig-to-primate kidney xenotransplantation after 5-hours of cold Ischemia

Hisadome et al. compare the impact of static cold storage or hypothermic machine perfusion of kidneys that are xenotransplanted from pig to primate. Hypothermic machine perfusion reduces ischemia-reperfusion injury, so may help prevent early xenograft failure.

Yu Hisadome
Daniel L. Eisenson
Kazuhiko Yamada
ResearchOpen Access15 Apr 2025
Communications Medicine

Volume: 5, P: 1-10
Deep learning for diagnosis of acute promyelocytic leukemia via recognition of genomically imprinted morphologic features

John-William Sidhom
Ingharan J. Siddarthan
Eugene Shenderov
ResearchOpen Access14 May 2021
npj Precision Oncology

Volume: 5, P: 1-8
Immunomodulatory response to neoadjuvant nivolumab in non-metastatic clear cell renal cell carcinoma

Nirmish Singla
Thomas R. Nirschl
Charles G. Drake
ResearchOpen Access17 Jan 2024
Scientific Reports

Volume: 14, P: 1-16
Divergent immune microenvironments in two tumor nodules from a patient with mismatch repair-deficient prostate cancer

Hannah E. Bergom
Laura A. Sena
Emmanuel S. Antonarakis
ResearchOpen Access22 Jan 2024
npj Genomic Medicine

Volume: 9, P: 1-9

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Neoadjuvant enoblituzumab in localized prostate cancer: a single-arm, phase 2 trial

Hypothermic machine perfusion prevents hyperacute graft loss in pig-to-primate kidney xenotransplantation after 5-hours of cold Ischemia

Deep learning for diagnosis of acute promyelocytic leukemia via recognition of genomically imprinted morphologic features

Immunomodulatory response to neoadjuvant nivolumab in non-metastatic clear cell renal cell carcinoma

Divergent immune microenvironments in two tumor nodules from a patient with mismatch repair-deficient prostate cancer

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