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Clade-specific extracellular vesicles from Akkermansia muciniphila mediate competitive colonization via direct inhibition and immune stimulation

Akkermansia muciniphila has several clades (AmI-AmIV), with one clade usually dominating per host. Here, the authors show AmII-derived extracellular vesicles mediate competitive exclusion of AmI via direct inhibition and immune stimulation.

Moon-Gi Hong
Eun-Ji Song
Young-Do Nam
ResearchOpen Access19 Mar 2025
Nature Communications

Volume: 16, P: 1-16
High-throughput evaluation of in vitro CRISPR activities enables optimized large-scale multiplex enrichment of rare variants

Cut-seq1, Cut-seq2, DeepCut and CLOVE-seq methods find optimized single-guide RNAs to detect a large number of rare variants in cells.

Joo Hye Yeo
Seungho Lee
Hyongbum Henry Kim
Research30 Oct 2025
Nature Biomedical Engineering

P: 1-21
Comparative evaluation of two herbal formulas for gastrointestinal function and gut microbiota modulation in rats with loperamide-induced dyspepsia

Saeid Khakisahneh
Jing-Hua Wang
Hojun Kim
ResearchOpen Access25 Aug 2025
Scientific Reports

Volume: 15, P: 1-13
Endoscopic Transplantation of Mesenchymal Stem Cell Sheets in Experimental Colitis in Rats

Sehyung Pak
Sung Wook Hwang
Seung-Jae Myung
ResearchOpen Access27 Jul 2018
Scientific Reports

Volume: 8, P: 1-11
Ginseng extracts improve circadian clock gene expression and reduce inflammation directly and indirectly through gut microbiota and PI3K signaling pathway

Xue-Ying Zhang
Saeid Khakisahneh
Hojun Kim
ResearchOpen Access19 Mar 2024
npj Biofilms and Microbiomes

Volume: 10, P: 1-14
Yijung-tang improves thermogenesis and reduces inflammation associated with gut microbiota in hypothyroid rats

Saeid Khakisahneh
Xue-Ying Zhang
Hojun Kim
ResearchOpen Access03 Jun 2023
npj Biofilms and Microbiomes

Volume: 9, P: 1-14
Phenylacetic acid, an anti-vaginitis metabolite produced by the vaginal symbiotic bacterium Chryseobacterium gleum

Kang Mu Kwon
Eun-Hye Kim
In Hyun Hwang
ResearchOpen Access28 May 2024
Scientific Reports

Volume: 14, P: 1-12
Ssu72 is a T-cell receptor-responsive modifier that is indispensable for regulatory T cells

Jin-Kwan Lee
Seo-Young Koo
Chang-Woo Lee
Research13 Apr 2021
Cellular & Molecular Immunology

Volume: 18, P: 1395-1411
Stochastic anomaly of methylome but persistent SRY hypermethylation in disorder of sex development in canine somatic cell nuclear transfer

Young-Hee Jeong
Hanlin Lu
Fei Gao
ResearchOpen Access09 Aug 2016
Scientific Reports

Volume: 6, P: 1-11
Occurrence of viable, red-pigmented haloarchaea in the plumage of captive flamingoes

Kyung June Yim
Joseph Kwon
Seong Woon Roh
ResearchOpen Access10 Nov 2015
Scientific Reports

Volume: 5, P: 1-10
The effects of sequencing platforms on phylogenetic resolution in 16 S rRNA gene profiling of human feces

Tae Woong Whon
Won-Hyong Chung
Young-Do Nam
ResearchOpen Access24 Apr 2018
Scientific Data

Volume: 5, P: 1-15
Intrahippocampal injection of a lentiviral vector expressing neurogranin enhances cognitive function in 5XFAD mice

Seong Gak Jeon
Moonkyung Kang
Minho Moon
ResearchOpen Access23 Mar 2018
Experimental & Molecular Medicine

Volume: 50, P: e461

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Clade-specific extracellular vesicles from Akkermansia muciniphila mediate competitive colonization via direct inhibition and immune stimulation

High-throughput evaluation of in vitro CRISPR activities enables optimized large-scale multiplex enrichment of rare variants

Comparative evaluation of two herbal formulas for gastrointestinal function and gut microbiota modulation in rats with loperamide-induced dyspepsia

Endoscopic Transplantation of Mesenchymal Stem Cell Sheets in Experimental Colitis in Rats

Ginseng extracts improve circadian clock gene expression and reduce inflammation directly and indirectly through gut microbiota and PI3K signaling pathway

Yijung-tang improves thermogenesis and reduces inflammation associated with gut microbiota in hypothyroid rats

Phenylacetic acid, an anti-vaginitis metabolite produced by the vaginal symbiotic bacterium Chryseobacterium gleum

Ssu72 is a T-cell receptor-responsive modifier that is indispensable for regulatory T cells

Stochastic anomaly of methylome but persistent SRY hypermethylation in disorder of sex development in canine somatic cell nuclear transfer

Occurrence of viable, red-pigmented haloarchaea in the plumage of captive flamingoes

The effects of sequencing platforms on phylogenetic resolution in 16 S rRNA gene profiling of human feces

Intrahippocampal injection of a lentiviral vector expressing neurogranin enhances cognitive function in 5XFAD mice

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