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Showing 1–9 of 9 results
Advanced filters: Author: Evan Haines Clear advanced filters

  • The APOE-ε4 allele is the strongest genetic risk factor for late-onset Alzheimer’s disease, but it is not deterministic. Here, the authors show that common genetic variation changes how APOE-ε4 influences cognition.

    • Alex G. Contreras
    • Skylar Walters
    • Timothy J. Hohman
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-17

  • Three-terminal memtransistors can improve the neuromorphic performance of conventional two-terminal memristors. Here, the authors report the fabrication of high-yield large-scale crossbar array architectures incorporating up to 2,048 2D MoS2 memtransistors per array, showing low-power memory and image recognition applications.

    • Thomas F. Schranghamer
    • Andrew Pannone
    • Saptarshi Das
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • A dataset of coding variation, derived from exome sequencing of nearly one million individuals from a range of ancestries, provides insight into rare variants and could accelerate the discovery of disease-associated genes and advance precision medicine efforts.

    • Kathie Y. Sun
    • Xiaodong Bai
    • Suganthi Balasubramanian
    ResearchOpen Access
    Nature
    Volume: 631, P: 583-592

  • Marsupial mammals take much longer to develop than similarly sized placental mammals, though how brain development occurs across these different periods is unclear. Here they show that the neurodevelopmental events of cortical neurogenesis, cell migration and axon extension do not all temporally scale to the same extent.

    • Annalisa Paolino
    • Elizabeth H. Haines
    • Laura R. Fenlon
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17

  • Genomic studies often lack representation from diverse populations, limiting equitable insights. Here, the authors show that the BIG Initiative captures extensive genetic diversity and reveals ancestry-linked health disparities in a community-based Mid-South cohort.

    • Silvia Buonaiuto
    • Franco Marsico
    • Vincenza Colonna
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-12

  • Developmental disorders (DDs) are more prevalent in males, thought to be due to X-linked genetic variation. Here, the authors investigate the burden of X-linked coding variants in 11,044 DD patients, showing that this contributes to ~6% of both male and female cases and therefore does not solely explain male bias in DDs.

    • Hilary C. Martin
    • Eugene J. Gardner
    • Matthew E. Hurles
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13