Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–2 of 2 results
Advanced filters: Author: Ewelina P. Owczarek Clear advanced filters

  • Immunoglobulin class switch recombination requires the activity of the RNA-degrading enzyme DIS3, and mutations affecting DIS3 exoribonucleolytic activity are common in multiple myeloma, implying that these dominant variants could be causal to B lymphoid tumorigenesis. Here the authors generate knock-in mice carrying the human DIS3 G766R mutation, which leads to plasmacytoid tumorigenesis via impairing the precision of AID-targeting.

    • Tomasz M. Kuliński
    • Olga Gewartowska
    • Andrzej Dziembowski
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-21

  • Upon intramuscular administration, COVID-19 mRNA vaccines are primarily taken up by macrophages, in which the cellular machinery extends their poly(A) tails, thereby increasing mRNA stability and translation, providing an explanation for the efficacy of these vaccines.

    • Paweł S. Krawczyk
    • Michał Mazur
    • Seweryn Mroczek
    ResearchOpen Access
    Nature
    Volume: 641, P: 984-992