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Showing 1–2 of 2 results
Advanced filters: Author: F. Faddoul Clear advanced filters

  • Anti-retroviral treatment does not fully resolve mucosal dysfunction and systemic inflammation in HIV infected individuals. Authors show here that an unusual population of regulatory T cells, distinguished by Amphiregulin expression and the incapability to suppress CD4 T cells might contribute to disrupted oral immune protection in HIV patients.

    • N. Bhaskaran
    • E. Schneider
    • P. Pandiyan
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15

  • Polyamine metabolism is a determinant of T helper cell polarization. Here, Mahalingam et al analyse the metabolic and transcriptomic profile of oral mucosa from people living with HIV to demonstrate the effect of polyamine synthesis on T cell dysfunction during HIV-1 infection.

    • S. S. Mahalingam
    • S. Jayaraman
    • P. Pandiyan
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15