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Showing 1–10 of 10 results
Advanced filters: Author: Fabian Rost Clear advanced filters

  • Hepatocyte organoids derived directly from human tissue enable long-term hepatocyte expansion and can be combined with portal mesenchyme and cholangiocyte organoids to form a donor-specific periportal liver assembloid system.

    • Lei Yuan
    • Sagarika Dawka
    • Meritxell Huch
    ResearchOpen Access
    Nature
    Volume: 650, P: 438-449

  • Therapeutic interference with the immune response after myocardial infarction holds the potential to close a clinically relevant gap. Here, the authors show that inhibition of a cardiomyocyte-specific ADAM10 / CX3CL1 axis improves post infarction survival and cardiac function by attenuating neutrophil-mediated myocardial damage.

    • Erik Klapproth
    • Anke Witt
    • Ali El-Armouche
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-14

  • Authors report that long-term intestinal tissue maintenance in naked mole rats is achieved by having an expanded pool of slow-dividing adult stem cells while a higher proportion of differentiated cells confer enhanced function and protection to the intestinal mucosa.

    • Shamir Montazid
    • Sheila Bandyopadhyay
    • Shazia Irshad
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-20

  • The phase diagram of the unconventional superconductor Sr2RuO4 in both normal and superconducting states is mapped out using high-precision measurements of the elastocaloric effect, showing similarities to other unconventional superconductors as well as unique features.

    • You-Sheng Li
    • Markus Garst
    • Andrew P. Mackenzie
    ResearchOpen Access
    Nature
    Volume: 607, P: 276-280

  • OpenMS is a flexible, user-friendly, open-source software platform for the biological analysis of mass spectrometry proteomics and metabolomics data. The modular platform allows developers to seamlessly generate custom data-analysis workflows and directly make such ready-made workflows available to biologist end-users. Also in this issue, see the Perspective by Tyanova et al.

    • Hannes L Röst
    • Timo Sachsenberg
    • Oliver Kohlbacher
    Reviews
    Nature Methods
    Volume: 13, P: 741-748

  • Lipofuscin labeling and 14 C retrospective birth-dating of neurons, along with mathematical modelling, here suggest continued postnatal neurogenesis in the human amygdala, rather than protracted maturation of developmentally generated neurons.

    • Sebastian S. Roeder
    • Petra Burkardt
    • Hagen B. Huttner
    ResearchOpen Access
    Communications Biology
    Volume: 5, P: 1-8

  • This protocol describes an approach for screening DNA-encoded chemical libraries (DECLs) to identify molecules that bind to proteins of interest. After isolating binding library members, DNA barcodes are amplified and identified by high-throughput sequencing.

    • Willy Decurtins
    • Moreno Wichert
    • Jörg Scheuermann
    Protocols
    Nature Protocols
    Volume: 11, P: 764-780