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Showing 1–2 of 2 results
Advanced filters: Author: Fabiane Sonego Clear advanced filters

  • The treatment options for sepsis are limited in scope and efficacy, resulting in frequent human fatalities. Liew and colleagues now report that interleukin-33 is a promising therapeutic strategy that increases neutrophil recruitment to the site of infection and bacterial clearance and decreases mortality in a mouse model of sepsis.

    • Jose C Alves-Filho
    • Fabiane Sônego
    • Foo Y Liew
    Research
    Nature Medicine
    Volume: 16, P: 708-712

  • Th9 cells are a subset of T helper cells that protect hosts against helminthic infection, but can also mediate allergic disease through overexpression of the cytokine IL-9. Here, Niedbala et al.show that nitric oxide is a potent enhancer of Th9 differentiation via the activation of p53 protein.

    • Wanda Niedbala
    • Anne-Gaelle Besnard
    • Foo Y. Liew
    Research
    Nature Communications
    Volume: 5, P: 1-13