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Showing 1–10 of 10 results
Advanced filters: Author: Fabienne Aujard Clear advanced filters

  • Together with a companion paper, the generation of a transcriptomic atlas for the mouse lemur and analyses of example cell types establish this animal as a molecularly tractable primate model organism.

    • Antoine de Morree
    • Iwijn De Vlaminck
    • Mark A. Krasnow
    ResearchOpen Access
    Nature
    Volume: 644, P: 173-184

  • Together with an accompanying paper presenting a transcriptomic atlas of the mouse lemur, interrogation of the atlas provides a rich body of data to support the use of the organism as a model for primate biology and health.

    • Camille Ezran
    • Shixuan Liu
    • Mark A. Krasnow
    ResearchOpen Access
    Nature
    Volume: 644, P: 185-196

  • EthoLoop enables real-time tracking and behavioral analysis of animals in naturalistic environments and can be combined with behavioral conditioning, optogenetic stimulation or wireless recording of neural activity. The system is illustrated with freely behaving mice and mouse lemurs.

    • Ali Nourizonoz
    • Robert Zimmermann
    • Daniel Huber
    Research
    Nature Methods
    Volume: 17, P: 1052-1059

  • Fabien Pifferi et al. report survival and age-related brain atrophy data in grey mouse lemurs fed either a normal diet or a diet restricted in calories by 30%. They find that caloric restriction extended life span by 50% and decelerated brain white matter atrophy, but accelerated the loss of grey matter, in most of the cerebrum.

    • Fabien Pifferi
    • Jérémy Terrien
    • Fabienne Aujard
    ResearchOpen Access
    Communications Biology
    Volume: 1, P: 1-8

  • Fabien Pifferi et al. discuss the latest research in using caloric restriction for promoting healthspan and lifespan in primates. Their Comment touches on their previous study, addressing how to combine nutrition-based clinical protocols with interventions to delay the onset of age-related diseases.

    • Fabien Pifferi
    • Jérémy Terrien
    • Fabienne Aujard
    Comments & OpinionOpen Access
    Communications Biology
    Volume: 2, P: 1-3

  • Endocrinologists have traditionally focused on studying one hormone or organ system at a time. Here the authors use transcriptomic data from the mouse lemur to globally characterize primate hormonal signaling, describing hormone sources and targets, identifying conserved and primate specific regulation, and elucidating principles of the network.

    • Shixuan Liu
    • Camille Ezran
    • James E. Ferrell Jr.
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-27