The catalytic hydrogenation of amides continues to be one of the most difficult reductive transformations in organic synthesis. Here, the authors report Ru-catalyzed hydrogenation of industrially relevant, functionalized, and structurally diverse aromatic, heterocyclic and aliphatic primary amides to produce the corresponding primary amines.
- Chakreshwara Kuloor
- Vishakha Goyal
- Rajenahally V. Jagadeesh
