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Advanced filters: Author: Fangyan Dai Clear advanced filters

  • A cell-autonomous role for the COUP-TFII transcription factor in prostate cancer cells is identified, in which COUP-TFII inhibits TGF-β signalling by binding to SMAD4; COUP-TFII promotes prostate tumorigenesis and metastasis in a mouse model, and is associated with more aggressive disease in human prostate cancers.

    • Jun Qin
    • San-Pin Wu
    • Sophia Y. Tsai
    Research
    Nature
    Volume: 493, P: 236-240