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Showing 1–3 of 3 results
Advanced filters: Author: Faraz I. Zaidi Clear advanced filters

  • Geospatial estimates of the prevalence of anemia in women of reproductive age across 82 low-income and middle-income countries reveals considerable heterogeneity and inequality at national and subnational levels, with few countries on track to meet the WHO Global Nutrition Targets by 2030.

    • Damaris Kinyoki
    • Aaron E. Osgood-Zimmerman
    • Simon I. Hay
    ResearchOpen Access
    Nature Medicine
    Volume: 27, P: 1761-1782

  • HIV envelope is a target for vaccine development, but induction of broadly neutralizing antibodies has been difficult. Here, the authors show that electroporation with a synthetic DNA vaccine construct allows in vivo production of HIV envelope native like trimers to induce autologous tier-2 neutralizing antibodies targeting a C3/V5 epitope in mice.

    • Ziyang Xu
    • Susanne Walker
    • Daniel W. Kulp
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-18

  • There is currently no licensed SARS-CoV-2 vaccine. Here, the authors generate an optimized DNA vaccine candidate encoding the SARS-CoV-2 spike antigen, demonstrating induction of specific T cells and neutralizing antibody responses in mice and guinea pigs. These initial results support further development of this vaccine candidate.

    • Trevor R. F. Smith
    • Ami Patel
    • Kate E. Broderick
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13