The ubiquitin-like modifier SUMO is involved in many aspects of the cell cycle, but its dynamics during mitosis are unknown. Here, Pelisch et al.use C. elegans to show that SUMO accumulates on the metaphase plate and is required for proper chromosome alignment, and deconjugation is required to progress through the cell cycle.
- Federico Pelisch
- Remi Sonneville
- Ronald T. Hay
