Nature Search

Injured epithelial cell states impact kidney allograft survival after T-cell-mediated rejection

T-cell–mediated rejection (TCMR) remains a major cause of kidney transplant failure with incompletely understood mechanisms. Here the authors use single-nucleus RNA sequencing, spatial transcriptomics and immunofluorescence to show that injured kidney epithelial cell states associate with poor transplant outcomes after T-cell–mediated rejection.

Anna Maria Pfefferkorn
Lorenz Jahn
Christian Hinze
ResearchOpen Access28 Jan 2026
Nature Communications

Volume: 17, P: 1-19
Autophagy-regulated mitochondrial inheritance controls early CD8⁺ T cell fate commitment

Borsa et al. show that asymmetric T cell division after activation requires autophagy to promote mitochondrial turnover, with T cells inheriting older mitochondria showing decreased degradation, reduced memory potential and altered metabolism.

Mariana Borsa
Ana Victoria Lechuga-Vieco
Anna Katharina Simon
ResearchOpen Access19 Dec 2025
Nature Cell Biology

Volume: 28, P: 66-81
COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis

Single-cell analysis of COVID-19 patient samples identifies activated immune pathways that correlate with severe disease.

Robert Lorenz Chua
Soeren Lukassen
Roland Eils
Research26 Jun 2020
Nature Biotechnology

Volume: 38, P: 970-979
Signatures of Dirac fermion-mediated magnetic order

The spin texture of a topological insulator is defined by spin-momentum locked Dirac fermions in its non-trivial surface states. Here, Sessi et al. show how the spin texture of Bi₂Te₃may be modified by extremely dilute magnetic adatoms, with magnetic order mediated via the RKKY interaction.

Paolo Sessi
Felix Reis
Matthias Bode
Research30 Oct 2014
Nature Communications

Volume: 5, P: 1-8
Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche

Most intestinal organoid models do not accurately model the interactions between epithelial and stromal cells. Here they establish a colon assembloid system with epithelial and stromal cells and demonstrate that BMP signals from differentiating epithelial cells promote mesenchymal niche organization.

Manqiang Lin
Kimberly Hartl
Michael Sigal
ResearchOpen Access25 May 2023
Nature Communications

Volume: 14, P: 1-14
A comprehensive benchmark of active learning strategies with AutoML for small-sample regression in materials science

Jinghou Bi
Yuanhao Xu
Steffen Ihlenfeldt
ResearchOpen Access23 Oct 2025
Scientific Reports

Volume: 15, P: 1-16
Analyzing the link between anxiety and eating behavior as a potential pathway to eating-related health outcomes

Felix S. Hussenoeder
Ines Conrad
Steffi G. Riedel-Heller
ResearchOpen Access19 Jul 2021
Scientific Reports

Volume: 11, P: 1-7
Evidence for spinarons in Co adatoms

Despite the theoretical prediction of spinaron quasiparticles in artificial nanostructures, experimental evidence has not yet been seen. Now it has been observed in a hybrid system comprising Co atoms on a Cu(111) surface.

Felix Friedrich
Artem Odobesko
Matthias Bode
Research26 Oct 2023
Nature Physics

Volume: 20, P: 28-33
Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs

The proteasome regulates several important cellular processes and has been identified as a target for therapeutic interventions. Here the authors map the conformational and energy landscape of the 26S proteasome upon Oprozomib binding and uncover long-range allosteric effects that control the dynamic behaviour of the proteasome.

David Haselbach
Jil Schrader
Holger Stark
ResearchOpen Access25 May 2017
Nature Communications

Volume: 8, P: 1-8
Estimation of reference curves for brain atrophy and analysis of robustness to machine effects

Elodie Piot
Félix Renard
Maria Luisa Mandelli
ResearchOpen Access03 Oct 2025
Scientific Reports

Volume: 15, P: 1-21
Genome-wide macroevolutionary signatures of key innovations in butterflies colonizing new host plants

Arms races between herbivores and plants have likely affected their evolutionary histories, which could have led to their high diversity. Allio et al. find that butterflies shifting to new host plants have more adaptive molecular signatures across their genomes and show repeated bursts of speciation rates.

Rémi Allio
Benoit Nabholz
Fabien L. Condamine
ResearchOpen Access13 Jan 2021
Nature Communications

Volume: 12, P: 1-15
Genetic predisposition to mosaic Y chromosome loss in blood

A genome-wide association study of mosaic loss of chromosome Y (LOY) in UK Biobank participants identifies 156 genetic determinants of LOY, showing that LOY is associated with cancer and non-haematological health outcomes.

Deborah J. Thompson
Giulio Genovese
John R. B. Perry
Research20 Nov 2019
Nature

Volume: 575, P: 652-657
Preserving the evolutionary potential of floras in biodiversity hotspots

Phylogenetic diversity is decoupled from taxon diversity for the Cape Floristic Region of South Africa, a biodiversity hotspot. It turns out that the more species-rich western part of the Cape has lower evolutionary potential than the more neglected eastern part, with important consequences for conservation planning.

Félix Forest
Richard Grenyer
Vincent Savolainen
Research15 Feb 2007
Nature

Volume: 445, P: 757-760
Genome-wide association study identifies eight loci associated with blood pressure

Christopher Newton-Cheh and colleagues report a genome-wide association study for blood pressure traits as part of the Global BPgen consortium. They report eight loci with replicated association to systolic and/or diastolic blood pressure, with each also showing association to hypertension.

Christopher Newton-Cheh
Toby Johnson
Patricia B Munroe
Research10 May 2009
Nature Genetics

Volume: 41, P: 666-676
Benchmarking AutoML for regression tasks on small tabular data in materials design

Felix Conrad
Mauritz Mälzer
Steffen Ihlenfeldt
ResearchOpen Access11 Nov 2022
Scientific Reports

Volume: 12, P: 1-14
De novo mutations in HCN1 cause early infantile epileptic encephalopathy

Christel Depienne, Eric LeGuern and colleagues report the identification of 5 de novo missense mutations in HCN1 in individuals with early-onset epileptic encephalopathy. Functional studies confirmed the pathogenic nature of these mutations.

Caroline Nava
Carine Dalle
Christel Depienne
Research20 Apr 2014
Nature Genetics

Volume: 46, P: 640-645
Carbon flow from volcanic CO₂ into soil microbial communities of a wetland mofette

Felix Beulig
Verena B Heuer
Kirsten Küsel
Research12 Sept 2014
The ISME Journal

Volume: 9, P: 746-759
Phasic and sustained interactions of multisensory interplay and temporal expectation

Felix Ball
Fabienne Fuehrmann
Toemme Noesselt
ResearchOpen Access05 Jul 2018
Scientific Reports

Volume: 8, P: 1-12
Early warning of complex climate risk with integrated artificial intelligence

In the era of climate change, human societies face growing exposure to disasters and complex climate risks. This perspective explores the transformative potential of integrated Artificial Intelligence in developing multi-hazard Early Warning Systems for all.

Markus Reichstein
Vitus Benson
Kommy Weldemariam
ReviewsOpen Access15 Mar 2025
Nature Communications

Volume: 16, P: 1-13
Quantification of the ozone and singlet delta oxygen produced in gas and liquid phases by a non-thermal atmospheric plasma with relevance for medical treatment

Helena Jablonowski
Joao Santos Sousa
Stephan Reuter
ResearchOpen Access15 Aug 2018
Scientific Reports

Volume: 8, P: 1-12
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
Adrenomedullary function, obesity and permissive influences of catecholamines on body mass in patients with chromaffin cell tumours

Yaxin An
Manja Reimann
Graeme Eisenhofer
Research03 Mar 2018
International Journal of Obesity

Volume: 43, P: 263-275
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22

Search

Injured epithelial cell states impact kidney allograft survival after T-cell-mediated rejection

Autophagy-regulated mitochondrial inheritance controls early CD8⁺ T cell fate commitment

COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis

Signatures of Dirac fermion-mediated magnetic order

Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche

A comprehensive benchmark of active learning strategies with AutoML for small-sample regression in materials science

Analyzing the link between anxiety and eating behavior as a potential pathway to eating-related health outcomes

Evidence for spinarons in Co adatoms

Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs

Estimation of reference curves for brain atrophy and analysis of robustness to machine effects

Genome-wide macroevolutionary signatures of key innovations in butterflies colonizing new host plants

Genetic predisposition to mosaic Y chromosome loss in blood

Preserving the evolutionary potential of floras in biodiversity hotspots

Genome-wide association study identifies eight loci associated with blood pressure

Benchmarking AutoML for regression tasks on small tabular data in materials design

De novo mutations in HCN1 cause early infantile epileptic encephalopathy

Carbon flow from volcanic CO₂ into soil microbial communities of a wetland mofette

Phasic and sustained interactions of multisensory interplay and temporal expectation

Early warning of complex climate risk with integrated artificial intelligence

Quantification of the ozone and singlet delta oxygen produced in gas and liquid phases by a non-thermal atmospheric plasma with relevance for medical treatment

At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Adrenomedullary function, obesity and permissive influences of catecholamines on body mass in patients with chromaffin cell tumours

ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

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