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Showing 1–6 of 6 results
Advanced filters: Author: Felix H Schacher Clear advanced filters

  • Physico-chemical properties of the cargo as well as the actual conditions during encapsulation interfere during formulation of nanoparticular cargo–carrier systems. We demonstrate altered chain conformations in the different micelles due to different cargo–carrier interactions leading to different localization of model drugs within the carrier. Finally, these changes lead to differences in pharmacokinetics and biodistribution in vivo, showing the relevance of such effects in a translational manner.

    • Adrian T Press
    • Anuradha Ramoji
    • Michael Bauer
    ResearchOpen Access
    NPG Asia Materials
    Volume: 9, P: e444

  • Multicompartment micelles can be assembled from block copolymers but it is difficult to manipulate their hierarchical superstructures using straightforward concepts. Here, methods are developed that involve the pre-assembly of subunits for the structurally controlled production of micelles.

    • André H. Gröschel
    • Felix H. Schacher
    • Axel H.E. Müller
    ResearchOpen Access
    Nature Communications
    Volume: 3, P: 1-10

  • Nacre-mimetics hold great promise as high-performance, functional materials. Here, the authors use synthetic nanoclays and demonstrate tuneable mechanical properties by varying the nanoclay aspect ratio, and suggest a transparent gas barrier application.

    • Paramita Das
    • Jani-Markus Malho
    • Andreas Walther
    Research
    Nature Communications
    Volume: 6, P: 1-14

  • Different polymers can be used in combination to produce coexisting nanoparticles of different symmetry and tailored to co-assemble into well-ordered binary and ternary hierarchical structures.

    • André H. Gröschel
    • Andreas Walther
    • Axel H. E. Müller
    Research
    Nature
    Volume: 503, P: 247-251

  • This Review discusses how organ-on-chip models can applied for infectious disease research.

    • Raquel Alonso-Roman
    • Alexander S. Mosig
    • Mark S. Gresnigt
    Reviews
    Nature Microbiology
    Volume: 9, P: 891-904