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Showing 1–6 of 6 results
Advanced filters: Author: Felix Ritort Clear advanced filters
  • Molecular shuttles are bi-stable and stimuli-responsive systems that are considered potential elements for molecular machinery. Here, the authors use optical tweezers to measure the force dependent real-time kinetics of individual molecular shuttles under aqueous conditions.

    • Teresa Naranjo
    • Kateryna M. Lemishko
    • Borja Ibarra
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-7
  • Short-lived kinetic states between equilibria are difficult to access experimentally, despite being crucial in many dynamical processes. Single-molecule experiments demonstrate that an extended fluctuation relation allows extraction of the free energies of these metastable states under non-equilibrium conditions.

    • Anna Alemany
    • Alessandro Mossa
    • Felix Ritort
    Research
    Nature Physics
    Volume: 8, P: 688-694
  • The helicases UvsW and RecG have both unwinding and rewinding activities and are involved in the rescue of stalled DNA replication forks. Here Manosas et al. use single-molecule techniques to characterize the rewinding activities of the two helicases, concluding that rewinding is actively catalysed.

    • Maria Manosas
    • Senthil K. Perumal
    • Vincent Croquette
    ResearchOpen Access
    Nature Communications
    Volume: 4, P: 1-12
  • Mapping the sequence specificity of DNA ligands remains a challenge, particularly for small drugs. Here the authors develop a parallelized single molecule magnetic tweezers approach using engineered DNA hairpins that can detect sequence selectivity, thermodynamics and kinetics of binding for small drugs and large proteins.

    • Maria Manosas
    • Joan Camunas-Soler
    • Felix Ritort
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-12
  • Anomalous-diffusion identifies the departure of diffusive dynamics from the traditional Brownian-motion and is a signature feature of a large number of complex soft-matter and biological systems. This article reports an analysis of an easy to implement method to decide on the type of an apparent anomaly, even in the presence of localisation errors.

    • Vittoria Sposini
    • Diego Krapf
    • Gleb Oshanin
    ResearchOpen Access
    Communications Physics
    Volume: 5, P: 1-10