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Showing 1–3 of 3 results
Advanced filters: Author: Ferdinand Greiss Clear advanced filters

  • Chromosomes are long DNA polymers, compacted in cells and fragile once released from the host. Here, authors report on a method to gently transplant bacterial chromosomes into 2D microfluidic compartments, enabling analysis of their conformations and function within a native transcription-translation system.

    • Ferdinand Greiss
    • Shirley S. Daube
    • Roy Bar-Ziv
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • Achieving genetic circuits on single DNA molecules could have varied applications. Here, authors observed proteins emerging from single DNA molecules through coupled transcription-translation complexes, and show that nascent proteins lingered on DNA, regulating cascaded reactions on the same DNA and allowing the design of a pulsatile genetic circuit.

    • Ferdinand Greiss
    • Nicolas Lardon
    • Roy Bar-Ziv
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-12

  • Building regulatory networks often requires trade-offs between accuracy and speed. Here the authors show in a bistable network the transition from a slow decision making system to a rapid one dominated by small number fluctuations.

    • Ferdinand Greiss
    • Shirley S. Daube
    • Roy Bar-Ziv
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-9