The role of DNA methylation on N6-adenine (6mA) in eukaryotes is a challenging research problem. Tan et al. develop a deep-learning-based algorithm to predict 6mA sites from sequences at single-nucleotide resolution, and apply the method to three representative model organisms. The method is further developed to visualize regulatory patterns around 6mA sites.
- Fei Tan
- Tian Tian
- Hakon Hakonarson
