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Advanced filters: Author: Filip M. Asscher Clear advanced filters

  • Eukaryotic DNA replication is regulated to ensure copying of the genome (only) once per cell cycle. Here the authors, using optical trapping and confocal microscopy, demonstrate the dynamics of the origin recognition complex and subsequent intermediates that lead up to the loading of an MCM helicase onto DNA.

    • Humberto Sánchez
    • Kaley McCluskey
    • Nynke H. Dekker
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12