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Showing 1–12 of 12 results
Advanced filters: Author: Filippo M. Rijli Clear advanced filters

  • The spatial arrangement of sensory receptors on the face is reiterated at each stage of the somatosensory pathway from the brainstem to the cortex. Rijli and colleagues discuss the molecular mechanisms by which somatotopic maps are formed in the brainstem.

    • Reha S. Erzurumlu
    • Yasunori Murakami
    • Filippo M. Rijli
    Reviews
    Nature Reviews Neuroscience
    Volume: 11, P: 252-263

  • The authors discovered a far distant genomic region containing multiple clusters of regulatory elements that drive coordinated Hoxa expression across chromatin topologically associating domains in cranial neural crest, and are required for patterning of facial structures.

    • Sandra Kessler
    • Maryline Minoux
    • Filippo M. Rijli
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-22

  • How sensory maps are formed in the brain is only partially understood. Here the authors describe spontaneous calcium waves that propagate across different sensory nuclei in the embryonic thalamus; disrupting the wave pattern triggers thalamic gene expression changes and eventually alters the size of cortical areas.

    • Verónica Moreno-Juan
    • Anton Filipchuk
    • Guillermina López-Bendito
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-14

  • Differences in facial morphology distinguish vertebrates. Here, Selleri and Rijli discuss advances in multi-omics and single-cell technologies linking genes, transcriptional networks and epigenetic landscapes to the establishment of facial patterning and its variation, with an emphasis on normal and abnormal craniofacial morphogenesis.

    • Licia Selleri
    • Filippo M. Rijli
    Reviews
    Nature Reviews Genetics
    Volume: 24, P: 610-626

  • Neural mechanisms underlying the construction of distinct barrel maps, and to what extent they rely on the type of sensory receptors are not fully understood. Here authors show that prenatal mystacial whisker ablation triggers a thalamic mechanism that rescales cortical territories, refining upper lip whisker barrels and enhancing sensory resolution, emphasizing a critical developmental process in sensory mapping.

    • Mar Aníbal-Martínez
    • Lorenzo Puche-Aroca
    • Guillermina López-Bendito
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-17

  • In vertebrates, the face is formed in part by neural crest cells. It has been assumed that the developmental fate of these cells is inbuilt. New work, however, reveals a role for instructive signals from nearby cells.

    • Massimo Pasqualetti
    • Filippo M. Rijli
    News & Views
    Nature
    Volume: 416, P: 493-494