Nature Search

Antigen-specific human antibodies from mice comprising four distinct genetic modifications

Nils Lonberg
Lisa D. Taylor
Dennis Huszar
Research28 Apr 1994
Nature

Volume: 368, P: 856-859
Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study

Turajlic and colleagues assess longitudinal antibody and cellular immune responses against SARS-CoV-2 variants of concern in patients with cancer, following either recovery from SARS-CoV-2 infection or vaccination, in two back-to-back reports from the CAPTURE study.

Annika Fendler
Scott T. C. Shepherd
Samra Turajlic
ResearchOpen Access27 Oct 2021
Nature Cancer

Volume: 2, P: 1305-1320
Whole-genome sequencing of a sporadic primary immunodeficiency cohort

Whole-genome sequencing analysis of individuals with primary immunodeficiency identifies new candidate disease-associated genes and shows how the interplay between genetic variants can explain the variable penetrance and complexity of the disease.

James E. D. Thaventhiran
Hana Lango Allen
Kenneth G. C. Smith
Research06 May 2020
Nature

Volume: 583, P: 90-95
Whole-genome sequencing of patients with rare diseases in a national health system

Whole-genome sequencing and phenotype data sharing are introduced in a national health system to streamline diagnosis and to discover coding and non-coding variants that cause rare diseases.

Ernest Turro
William J. Astle
Willem H. Ouwehand
Research24 Jun 2020
Nature

Volume: 583, P: 96-102
Strontium isoscape of sub-Saharan Africa allows tracing origins of victims of the transatlantic slave trade

Strontium isotope analysis can be applied to animal and plant tissues to help determine their provenance. Here, the authors generate a strontium isoscape of sub-Saharan Africa using data from 2266 environmental samples and demonstrate its efficacy by tracing the African roots of individuals from historic slavery contexts.

Xueye Wang
Gaëlle Bocksberger
Vicky M. Oelze
ResearchOpen Access30 Dec 2024
Nature Communications

Volume: 15, P: 1-14
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

A randomized trial in patients hospitalized with COVID-19 showed no benefit and potentially increased harm associated with the use of convalescent plasma, with subgroup analyses suggesting that the antibody profile in donor plasma is critical in determining clinical outcomes.

Philippe Bégin
Jeannie Callum
Donald M. Arnold
ResearchOpen Access09 Sept 2021
Nature Medicine

Volume: 27, P: 2012-2024
Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

Statins are effectively used to prevent and manage cardiovascular disease, but patient response to these drugs is highly variable. Here, the authors identify two new genes associated with the response of LDL cholesterol to statins and advance our understanding of the genetic basis of drug response.

Iris Postmus
Stella Trompet
Chris C. A. Spencer
ResearchOpen Access28 Oct 2014
Nature Communications

Volume: 5, P: 1-10
GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements

Investigation of variation in three cohorts has identified multiple genetic signals associated with the pregnancy-specific liver disorder, intrahepatic cholestasis of pregnancy, giving insight into the disease which can cause preterm birth and stillbirth.

Peter H. Dixon
Adam P. Levine
Catherine Williamson
ResearchOpen Access17 Aug 2022
Nature Communications

Volume: 13, P: 1-18
A glimpse of antimicrobial resistance gene diversity in kefir and yoghurt

Adrienn Gréta Tóth
István Csabai
Norbert Solymosi
ResearchOpen Access31 Dec 2020
Scientific Reports

Volume: 10, P: 1-12
Purinergic receptors in the carotid body as a new drug target for controlling hypertension

A small-molecule antagonist of the P2X3 receptor reduces blood pressure in hypertensive rats via its action on the carotid body, pointing to a new drug target for treating hypertension.

Wioletta Pijacka
Davi J A Moraes
Julian F R Paton
Research05 Sept 2016
Nature Medicine

Volume: 22, P: 1151-1159
Huntington disease-like 2: insight into neurodegeneration from an African disease

Huntington disease (HD)-like 2 (HDL2) is a rare HD phenocopy that seems to be confined to people with African ancestry. This Review summarizes our current knowledge of HDL2 and highlights the need for further studies of neurodegenerative diseases on the African continent.

Amanda Krause
David G. Anderson
Russell L. Margolis
Reviews19 Dec 2023
Nature Reviews Neurology

Volume: 20, P: 36-49
Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort

James E. D. Thaventhiran
Hana Lango Allen
Kenneth G. C. Smith
Amendments and Corrections17 Jul 2020
Nature

Volume: 584, P: E2
Unraveling the association between genetic integrity and metabolic activity in pre-implantation stage embryos

Fiona D’Souza
Shivanand M. Pudakalakatti
Satish Kumar Adiga
ResearchOpen Access17 Nov 2016
Scientific Reports

Volume: 6, P: 1-12
Spent embryo culture medium metabolites are related to the in vitro attachment ability of blastocysts

Fiona D’Souza
Shubhashree Uppangala
Satish Kumar Adiga
ResearchOpen Access19 Nov 2018
Scientific Reports

Volume: 8, P: 1-10
Author Correction: Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Amendments and CorrectionsOpen Access12 Jan 2022
Nature Medicine

Volume: 28, P: 212
Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Research10 Jan 2022
Nature Medicine

Volume: 28, P: 53-58
Early and intensive Motor Training for people with spinal cord injuries (the SCI-MT Trial): description of the intervention

M. Ben
J. V. Glinsky
L. A. Harvey
ResearchOpen Access19 Jul 2023
Spinal Cord

Volume: 61, P: 600-607
Do lower antenatal blood pressure cut-offs in pregnant women with obesity identify those at greater risk of adverse maternal and perinatal outcomes? A secondary analysis of data from the UK Pregnancies Better Eating and Activity Trial (UPBEAT)

L. Slade
N. Syeda
Patrick Catalano
ResearchOpen Access16 Jun 2025
International Journal of Obesity

Volume: 49, P: 1523-1531
Early and intensive motor training to enhance neurological recovery in people with spinal cord injury: trial protocol

Lisa A. Harvey
Joanne V. Glinsky
Sachin Shetty
ResearchOpen Access06 Jul 2023
Spinal Cord

Volume: 61, P: 521-527
Transcriptome profiles of stem-like cells from primary breast cancers allow identification of ITGA7 as a predictive marker of chemotherapy response

Noha Gwili
Stacey J. Jones
Thomas A. Hughes
ResearchOpen Access12 Jul 2021
British Journal of Cancer

Volume: 125, P: 983-993
Pathogenic stromal cells as therapeutic targets in joint inflammation

Stromal cells of mesenchymal origin can help to sustain inflammation in the joint by various mechanisms; understanding these mechanisms could inform new therapeutic strategies and explain why joint inflammation persists in diseases of the joint such as arthritis, enthesopathy and tendinopathy.

Stephanie G. Dakin
Mark Coles
Christopher D. Buckley
Reviews12 Nov 2018
Nature Reviews Rheumatology

Volume: 14, P: 714-726
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

Ewan Pearson and colleagues report a genome-wide association study for glycemic response to metformin in individuals with type 2 diabetes. They identify variants near ATM associated with treatment success.

Kaixin Zhou
Celine Bellenguez
Ewan R Pearson
Research26 Dec 2010
Nature Genetics

Volume: 43, P: 117-120
Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

Edward J Saunders
Tokhir Dadaev
Zsofia Kote-Jarai
ResearchOpen Access10 Mar 2016
British Journal of Cancer

Volume: 114, P: 945-952
Lifestyle intervention in obese pregnancy and cardiac remodelling in 3-year olds: children of the UPBEAT RCT

Paul D. Taylor
Haotian Gu
Lynne Greenwood
ResearchOpen Access12 Oct 2022
International Journal of Obesity

Volume: 46, P: 2145-2155
RGS9-2 Modulates Responses to Oxycodone in Pain-Free and Chronic Pain States

Sevasti Gaspari
Valeria Cogliani
Venetia Zachariou
Research11 Jan 2017
Neuropsychopharmacology

Volume: 42, P: 1548-1556
Nucleus Accumbens-Specific Interventions in RGS9-2 Activity Modulate Responses to Morphine

Sevasti Gaspari
Maria M Papachatzaki
Venetia Zachariou
Research24 Feb 2014
Neuropsychopharmacology

Volume: 39, P: 1968-1977

Search

Antigen-specific human antibodies from mice comprising four distinct genetic modifications

Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study

Whole-genome sequencing of a sporadic primary immunodeficiency cohort

Whole-genome sequencing of patients with rare diseases in a national health system

Strontium isoscape of sub-Saharan Africa allows tracing origins of victims of the transatlantic slave trade

Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements

A glimpse of antimicrobial resistance gene diversity in kefir and yoghurt

Purinergic receptors in the carotid body as a new drug target for controlling hypertension

Huntington disease-like 2: insight into neurodegeneration from an African disease

Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort

Unraveling the association between genetic integrity and metabolic activity in pre-implantation stage embryos

Spent embryo culture medium metabolites are related to the in vitro attachment ability of blastocysts

Author Correction: Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19

Early and intensive Motor Training for people with spinal cord injuries (the SCI-MT Trial): description of the intervention

Do lower antenatal blood pressure cut-offs in pregnant women with obesity identify those at greater risk of adverse maternal and perinatal outcomes? A secondary analysis of data from the UK Pregnancies Better Eating and Activity Trial (UPBEAT)

Early and intensive motor training to enhance neurological recovery in people with spinal cord injury: trial protocol

Transcriptome profiles of stem-like cells from primary breast cancers allow identification of ITGA7 as a predictive marker of chemotherapy response

Pathogenic stromal cells as therapeutic targets in joint inflammation

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

Lifestyle intervention in obese pregnancy and cardiac remodelling in 3-year olds: children of the UPBEAT RCT

RGS9-2 Modulates Responses to Oxycodone in Pain-Free and Chronic Pain States

Nucleus Accumbens-Specific Interventions in RGS9-2 Activity Modulate Responses to Morphine

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