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Showing 1–3 of 3 results

Advanced filters: Author: Fiona Pachl Clear advanced filters

DMSO enhances electrospray response, boosting sensitivity of proteomic experiments

The addition of a low percentage of DMSO into liquid chromatography solvents strongly enhances peptide electrospray ionization, substantially improving proteome analysis by liquid chromatography–tandem mass spectrometry.

Hannes Hahne
Fiona Pachl
Bernhard Kuster
Research25 Aug 2013
Nature Methods

Volume: 10, P: 989-991
Targeted protein degradation using chimeric human E2 ubiquitin-conjugating enzymes

Modifying an E2 ubiquitin-conjugating enzyme with a binding domain creates an encodable strategy for driving targeted protein degradation within eukaryotic cells.

Jonathan D. Taylor
Nathalie Barrett
Sandrine Legg
ResearchOpen Access19 Sept 2024
Communications Biology

Volume: 7, P: 1-17
Quantitative chemical proteomics reveals a Plk1 inhibitor-compromised cell death pathway in human cells

Monika Raab
Fiona Pachl
Klaus Strebhardt
CorrespondenceOpen Access01 Jul 2014
Cell Research

Volume: 24, P: 1141-1145