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Showing 1–2 of 2 results
Advanced filters: Author: Flavia Frattini Clear advanced filters

  • Disinhibition of neural activity in the spinal cord is implicated in neuropathic pain. Chen et al.show that disinhibition of neural activity arises from a shift in reversal potential of GABA and a decrease in the conductance of presynaptic GABA, which are both regulated by brain-derived neurotrophic factor.

    • Jeremy Tsung-chieh Chen
    • Da Guo
    • Jing Hu
    ResearchOpen Access
    Nature Communications
    Volume: 5, P: 1-14

  • To maintain viability, cells must be able to sense and respond to mechanical stimuli. Here, Qi et al. show that the STOML3 protein acts in mechanosensation by binding cholesterol and regulating membrane stiffness which can in turn regulate ion flux through mechanosensitive channels.

    • Yanmei Qi
    • Laura Andolfi
    • Jing Hu
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-13