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Advanced filters: Author: Florence Buseyne Clear advanced filters

The crystal structure of a simian Foamy Virus receptor binding domain provides clues about entry into host cells

Foamy viruses are ancient retroviruses that are prevalent in non-human primates. Fernández et al. report an X-ray structure of a protein domain from a simian Foamy virus that mediates the attachment to cells, providing insights into viral entry.

Ignacio Fernández
Lasse Toftdal Dynesen
Marija Backovic
ResearchOpen Access06 Mar 2023
Nature Communications

Volume: 14, P: 1-14
MHC-I–restricted presentation of HIV-1 virion antigens without viral replication

Florence Buseyne
Sylvie Le Gall
Olivier Schwartz
Research01 Mar 2001
Nature Medicine

Volume: 7, P: 344-349
Clonal succession after prolonged antiretroviral therapy rejuvenates CD8⁺ T cell responses against HIV-1

Appay and colleagues show that long-term antiretroviral therapy is associated with clonal succession of HIV-1-specific CD8⁺ T cell populations, which evolved from an exhaustion-like toward a stemness-like phenotype.

Eoghann White
Laura Papagno
Victor Appay
Research23 Aug 2024
Nature Immunology

Volume: 25, P: 1555-1564