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Showing 1–3 of 3 results
Advanced filters: Author: Florian M. Pauler Clear advanced filters
  • In most mammals, imprinted genes contain epigenetic marks that differ in each parental genome and control their parent-of-origin-specific expression. Here, the authors map imprinted genes in mouse preimplantation embryos and find that imprinted gene expression in blastocysts is mainly dependent on Polycomb-mediated H3K27me3-associated gene silencing.

    • Laura Santini
    • Florian Halbritter
    • Martin Leeb
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-16
  • A collection of single-gene-mutant human cells is described. This growing resource is based on gene-trap mutagenesis of a near-haploid human cell line and covers almost 3,500 human genes.

    • Tilmann Bürckstümmer
    • Carina Banning
    • Sebastian M B Nijman
    Research
    Nature Methods
    Volume: 10, P: 965-971