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Advanced filters: Author: Foteini Davrazou Clear advanced filters

  • One of four papers establishing certain PHD domains as effectors of trimethylated histone H3K4, a chromatin mark generally associated with active transcription.

    The interaction between H3K4me3 and the ING2 PHD domain is enhanced after DNA damage, recruiting the repressive complex to the promoters of proliferation genes.

    • Xiaobing Shi
    • Tao Hong
    • Or Gozani
    Research
    Nature
    Volume: 442, P: 96-99

  • One of four papers establishing certain PHD domains as effectors of trimethylated histone H3K4, a chromatin mark generally associated with active transcription. This paper describes the structure of the PHD finger from the tumour suppressor ING2 complexed with H3K4me3.

    • Pedro V. Peña
    • Foteini Davrazou
    • Tatiana G. Kutateladze
    Research
    Nature
    Volume: 442, P: 100-103