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Showing 1–2 of 2 results
Advanced filters: Author: Frédéric Fercoq Clear advanced filters

  • Effective anticancer adoptive cellular therapy (ACT) requires sufficient infiltration of injected cytotoxic lymphocytes, but pathophysiology frustrates this. Regulator of G protein signaling 1 limits T cell trafficking to breast tumors and may be targeted to improve ACT.

    • Frédéric Fercoq
    • Leo M. Carlin
    News & Views
    Nature Immunology
    Volume: 22, P: 802-804

  • Idiopathic pulmonary fibrosis has been associated with aberrant expansion of KRT5-expressing basal cells. Here the authors show how changes in the ECM glycoprotein SPARC restrict the movement of KRT5+ cells, affecting their retention within fibrotic tissue.

    • Richard J. Hewitt
    • Franz Puttur
    • Clare M. Lloyd
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-20