Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–6 of 6 results
Advanced filters: Author: Françoise Jacob-Dubuisson Clear advanced filters

  • Canonical two-component systems catalyse autophosphorylation of the histidine kinase, transfer of the phosphoryl group to the regulator and dephosphorylation of the phosphoregulator. In this Progress article, Jacob-Dubuisson and colleagues highlight recent structural insights into the signalling and catalytic mechanisms of sensor histidine kinases.

    • Françoise Jacob-Dubuisson
    • Ariel Mechaly
    • Rudy Antoine
    Reviews
    Nature Reviews Microbiology
    Volume: 16, P: 585-593

  • The fundamental processes of protein insertion and translocation at the outer membrane are mediated by Omp85 proteins. Here the authors report structures of the translocase FhaC, showing that the critical L6 loop adopts a conformation similar to that of related insertases; establishing a common structural basis for Omp85 function.

    • Timm Maier
    • Bernard Clantin
    • Vincent Villeret
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-9

  • The two-partner secretion system transports proteins across the bacterial outer membrane but the molecular mechanisms involved are poorly understood. Here, Baud et al. use site-specific crosslinking to track the path of a protein substrate through the β-barrel of its Omp85 transporter.

    • Catherine Baud
    • Jérémy Guérin
    • Françoise Jacob-Dubuisson
    Research
    Nature Communications
    Volume: 5, P: 1-9

  • The mechanisms of protein translocation across and integration into bacterial outer membranes are poorly understood. Here, Norell et al. reconstitute type-V secretion and β-barrel protein biogenesis in proteoliposomes providing a versatile cell-free system to study integration and translocation.

    • Derrick Norell
    • Alexander Heuck
    • Enguo Fan
    Research
    Nature Communications
    Volume: 5, P: 1-9

  • Alex Rivera-Millot et al. investigate copper homeostasis in the whooping cough agent Bordetella pertussis, which has a single copper defense mechanism via a metallochaperone diverted for copper passivation and two peroxide detoxification enzymes. This study demonstrates that copper up-regulates the copZ-prxgrx-gorB operon in macrophages, and this system appears to contribute to persistent infection in the nasal cavity of B. pertussis-infected mice. This study brings insight into strategies aimed to optimize survival of a host-restricted pathogen.

    • Alex Rivera-Millot
    • Stéphanie Slupek
    • Françoise Jacob-Dubuisson
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-12

  • LOV (light, oxygen or voltage) domains are conserved protein photosensors that detect blue light via a flavin cofactor. In this Review, Herrou and Crosson describe our current understanding of the function and signal transduction mechanisms of bacterial LOV proteins and discuss their potential use in synthetic biology.

    • Julien Herrou
    • Sean Crosson
    Reviews
    Nature Reviews Microbiology
    Volume: 9, P: 713-723