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Showing 51–81 of 81 results

Advanced filters: Author: Francesca Aria Clear advanced filters

PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA

Chromosomal rearrangements are key events in the pathogenesis of a range of disorders. Here the authors utilize a zinc finger nuclease translocation reporter to identify PARP3 as a regulator of these events at sites enriched for G quadruplex DNA.

Tovah A. Day
Jacob V. Layer
David M. Weinstock
ResearchOpen Access27 Apr 2017
Nature Communications

Volume: 8, P: 1-15
Beta cell-specific CD8⁺ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes

Autoreactive T cells are subject to continuous antigenic stimulation yet sustain their autoreactive functionality. Youngblood and colleagues examine type 1 diabetes systems to show that a pool of autoreactive CD8⁺ T cells exhibits a stem cell–like signature that facilitates their durable activity.

Hossam A. Abdelsamed
Caitlin C. Zebley
Ben Youngblood
Research30 Mar 2020
Nature Immunology

Volume: 21, P: 578-587
Solution structure of recombinant Pvfp-5β reveals insights into mussel adhesion

Solution structure of byssal plaque protein Pvfp-5β secreted by the Asian green mussel Perna viridis gives molecular insight into mussel adhesion on wet surfaces.

Maria Agnese Morando
Francesca Venturella
Caterina Alfano
ResearchOpen Access25 Jul 2022
Communications Biology

Volume: 5, P: 1-10
Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy

Melanoma patients harbouring BRAF^V600E mutation generally develop resistance to targeted therapy. In this study, the authors demonstrate that SREBP-1-mediated induction of lipid biosynthesis contributes to therapy resistance in BRAF mutant melanoma.

Ali Talebi
Jonas Dehairs
Johannes V. Swinnen
ResearchOpen Access27 Jun 2018
Nature Communications

Volume: 9, P: 1-11
IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies

Transcriptomic and histological profiling of gut biopsies from multiple independent cohorts of patients with inflammatory bowel disease identifies distinct histopathological, molecular and cellular features associated with treatment response, providing insights for patient stratification and precision therapy.

Matthias Friedrich
Mathilde Pohin
Fiona M. Powrie
ResearchOpen Access21 Oct 2021
Nature Medicine

Volume: 27, P: 1970-1981
Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia

In chronic myelogenous leukemia, leukemia stem cell function requires a microRNA that is provided by bone marrow endothelial cells.

Bin Zhang
Le Xuan Truong Nguyen
Guido Marcucci
Research05 Mar 2018
Nature Medicine

Volume: 24, P: 450-462
MicroRNAs 17-5p–20a–106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation

Laura Fontana
Elvira Pelosi
Cesare Peschle
Research24 Jun 2007
Nature Cell Biology

Volume: 9, P: 775-787
GABAergic signaling contributes to tumor cell invasion and poor overall survival in colorectal cancer

Carly Strelez
Francesca Battaglin
Shannon M. Mumenthaler
ResearchOpen Access24 Aug 2025
Oncogene

Volume: 44, P: 3924-3938
Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes

Benign prostatic hyperplasia (BPH) is one of the most common diseases affecting aging men with limited therapeutic options. In this study, the authors describe the molecular characterization of BPH performing genomic, transcriptomic and epigenetic analysis of 18 BPH cases.

Deli Liu
Jonathan E. Shoag
Christopher E. Barbieri
ResearchOpen Access24 Apr 2020
Nature Communications

Volume: 11, P: 1-9
Ischemic wound revascularization by the stromal vascular fraction relies on host-donor hybrid vessels

Roman Vuerich
Elena Groppa
Serena Zacchigna
ResearchOpen Access11 Feb 2023
npj Regenerative Medicine

Volume: 8, P: 1-15
A reference database enabling in-depth proteome and PTM analysis of mouse immune cells

Devon Siemes
Hannah Voss
Olga Shevchuk
ResearchOpen Access10 Apr 2025
Scientific Data

Volume: 12, P: 1-8
Differential stem- and progenitor-cell trafficking by prostaglandin E₂

Endogenous prostaglandin E₂ (PGE₂) is a potent regulator of haematopoietic stem cell (HSC) retention in the bone marrow; inhibition of endogenous PGE₂ signalling by non-steroidal anti-inflammatory drugs results in enhanced HSC and haematopoietic progenitor cell mobility via E-prostanoid 4 (EP4) receptor antagonism.

Jonathan Hoggatt
Khalid S. Mohammad
Louis M. Pelus
Research13 Mar 2013
Nature

Volume: 495, P: 365-369
Self-renewal and phenotypic conversion are the main physiological responses of macrophages to the endogenous estrogen surge

Giovanna Pepe
Daniele Braga
Elisabetta Vegeto
ResearchOpen Access20 Mar 2017
Scientific Reports

Volume: 7, P: 1-14
Transplanting rejuvenated blood stem cells extends lifespan of aged immunocompromised mice

Sara Montserrat-Vazquez
Noelle J. Ali
M. Carolina Florian
ResearchOpen Access29 Dec 2022
npj Regenerative Medicine

Volume: 7, P: 1-17
The impact of autophagy modulation on phenotype and survival of cardiac stromal cells under metabolic stress

Isotta Chimenti
Vittorio Picchio
Sebastiano Sciarretta
ResearchOpen Access01 Apr 2022
Cell Death Discovery

Volume: 8, P: 1-15
Β-blockers treatment of cardiac surgery patients enhances isolation and improves phenotype of cardiosphere-derived cells

Isotta Chimenti
Francesca Pagano
Giacomo Frati
ResearchOpen Access14 Nov 2016
Scientific Reports

Volume: 6, P: 1-13
β₂-AR inhibition enhances EGFR antibody efficacy hampering the oxidative stress response machinery

Vitale Del Vecchio
Luigi Mele
Vincenzo Desiderio
ResearchOpen Access19 Sept 2023
Cell Death & Disease

Volume: 14, P: 1-10
Human adipose stem cell differentiation is highly affected by cancer cells both in vitro and in vivo: implication for autologous fat grafting

Francesca Paino
Marcella La Noce
Virginia Tirino
ResearchOpen Access19 Jan 2017
Cell Death & Disease

Volume: 8, P: e2568
HSP70 upregulation in nasal mucosa of symptomatic children with allergic rhinitis and potential risk of asthma development

Anna Fagotti
Livia Lucentini
Giuseppe Di Cara
ResearchOpen Access18 Aug 2022
Scientific Reports

Volume: 12, P: 1-10
ERα-LBD, an isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance

Antonio Strillacci
Pasquale Sansone
Jacqueline Bromberg
ResearchOpen Access23 Aug 2022
npj Breast Cancer

Volume: 8, P: 1-16
Spred1 deficit promotes treatment resistance and transformation of chronic phase CML

Junjing Qiao
Chen Liang
Guido Marcucci
Research25 Sept 2021
Leukemia

Volume: 36, P: 492-506
Increased frequency of activated CD8⁺ T cell effectors in patients with psoriatic arthritis

Marco Diani
Fabio Casciano
Eva Reali
ResearchOpen Access26 Jul 2019
Scientific Reports

Volume: 9, P: 1-10
Soluble TRAIL Armed Human MSC As Gene Therapy For Pancreatic Cancer

Carlotta Spano
Giulia Grisendi
Massimo Dominici
ResearchOpen Access11 Feb 2019
Scientific Reports

Volume: 9, P: 1-14
Blood-derived extracellular vesicles isolated from healthy donors exposed to air pollution modulate in vitro endothelial cells behavior

Federica Rota
Luca Ferrari
Valentina Bollati
ResearchOpen Access18 Nov 2020
Scientific Reports

Volume: 10, P: 1-11
Presynaptic dysfunction in CASK-related neurodevelopmental disorders

Martin Becker
Francesca Mastropasqua
Kristiina Tammimies
ResearchOpen Access14 Sept 2020
Translational Psychiatry

Volume: 10, P: 1-17
Golgi stress mediates redox imbalance and ferroptosis in human cells

Hamed Alborzinia et al. show that Golgi-dispersing compounds trigger iron-dependent oxidative degradation of lipids, inducing a non-apoptotic cell death called ferroptosis. This study provides insight into the role of Golgi apparatus for preventing ferroptotic cell death through its cellular redox control.

Hamed Alborzinia
Tatiana I. Ignashkova
Jan H. Reiling
ResearchOpen Access28 Nov 2018
Communications Biology

Volume: 1, P: 1-15
Ex.50.T aptamer impairs tumor–stroma cross-talk in breast cancer by targeting gremlin-1

Cristina Quintavalle
Francesco Ingenito
Gerolama Condorelli
ResearchOpen Access11 Mar 2025
Cell Death Discovery

Volume: 11, P: 1-16
Continuity in morphological disparity in tropical reef fishes across evolutionary scales

Morphological disparity in tropical reef fishes links intra- and interspecific variation, shaped by ecological and evolutionary processes. Dispersal traits promote genetic diversity and disparity, highlighting their role in gene flow and morphological evolution.

Giulia Francesca Azzurra Donati
Camille Albouy
Loïc Pellissier
ResearchOpen Access17 Feb 2025
Communications Biology

Volume: 8, P: 1-10
Muscle stem cells and fibro-adipogenic progenitors in female pelvic floor muscle regeneration following birth injury

Francesca Boscolo Sesillo
Varsha Rajesh
Marianna Alperin
ResearchOpen Access16 Dec 2022
npj Regenerative Medicine

Volume: 7, P: 1-12
Specific profile of ultrasonic communication in a mouse model of neurodevelopmental disorders

Marika Premoli
Sara Anna Bonini
Maurizio Memo
ResearchOpen Access04 Nov 2019
Scientific Reports

Volume: 9, P: 1-12
MicroRNAs-143 and -145 induce epithelial to mesenchymal transition and modulate the expression of junction proteins

Lidia Avalle
Danny Incarnato
Valeria Poli
Research23 Jun 2017
Cell Death & Differentiation

Volume: 24, P: 1750-1760

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