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Showing 1–3 of 3 results
Advanced filters: Author: Francesca Corlazzoli Clear advanced filters
  • When 100 social and behavioural science claims were examined, 34% of reanalyses closely matched the original results, with 74% reaching the same conclusion, revealing limited robustness of single-path analyses and the need to address analytical uncertainty.

    • Balazs Aczel
    • Barnabas Szaszi
    • Brian A. Nosek
    Research
    Nature
    Volume: 652, P: 135-142
  • Seguin et al demonstrated in glioblastoma patient-derived stem cells that a subset of glioblastoma tumours is dependent on macropinocytosis mediated survival through a Galectin-3/RAB10/beta 1 integrin axis. They used both genetic and pharmacologic inhibition of Galectin-3 in vivo and in vitro to identify underlying mechanisms and define a Galectin-3/macropinocytosis molecular signature, which could inform the development of anti-tumour therapeutic strategies.

    • Laetitia Seguin
    • Soline Odouard
    • Érika Cosset
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-17