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Showing 1–3 of 3 results

Advanced filters: Author: Francesca Picco Clear advanced filters

An in vivo and in vitro spatiotemporal profile of human midbrain development

This study provides a comprehensive profile of human fetal midbrain development and its comparison with lab-grown midbrain cultures. These findings demonstrate that midbrain organoids recapitulate fetal developmental stages while capturing essential spatial and molecular characteristics, relevant to dopamine-related disorders.

Dimitri Budinger
Pau Puigdevall
Serena Barral
ResearchOpen Access03 Feb 2026
Nature Communications

P: 1-25
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets

Precision oncology relies on model systems that reflect the genomic heterogeneity of human cancers. Here the authors characterize a panel of 151 colorectal cancer cell lines with respect to genetic mutations, expression profiles and drug sensitivity to identify new therapeutic targets.

Enzo Medico
Mariangela Russo
Alberto Bardelli
Research30 Apr 2015
Nature Communications

Volume: 6, P: 1-10
Identification of a novel minor-groove DNA binder that represses mitochondrial gene expression and induces apoptosis in highly aggressive leiomyosarcoma cells

Eleonora Malavasi
Raffaella Picco
Claudio Brancolini
ResearchOpen Access10 Nov 2025
Cell Death Discovery

Volume: 11, P: 1-17

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