Gram-negative bacteria use a multiprotein complex, LptB2FGC, to transport lipopolysaccharides (LPS) to the outer membrane. Here, Fiorentino et al. present cryo-EM structures of the complex from Pseudomonas aeruginosa, revealing species-specific features and providing insights into LPS transport mechanisms.
- Francesco Fiorentino
- Matteo Cervoni
- Jani R. Bolla