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Showing 1–6 of 6 results
Advanced filters: Author: Franz G. Zingl Clear advanced filters

  • Vibrio cholerae O1 outbreak strains are classified as Ogawa or Inaba serotypes, but the impact of serotype on pathogenicity is understudied. Here, the authors show that O1 antigen methylation in Ogawa strains promotes colonization and infectivity.

    • Franz G. Zingl
    • Deborah R. Leitner
    • Matthew K. Waldor
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-8

  • Oral vaccines against Vibrio cholera have been critical for cholera management, but the production of more efficacious and cost-effective approaches is still needed. Here the authors deliver a bivalent VHH construct that binds to cholera toxin and show protection in a murine cholera model.

    • Marcus Petersson
    • Franz G. Zingl
    • Sandra Wingaard Thrane
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • The Citrobacter rodentium CRISPR–Cas system is activated by the oxygen-responsive transcriptional regulator Fnr in the anoxic environment of the mouse gut.

    • Ian W. Campbell
    • David W. Basta
    • Matthew K. Waldor
    ResearchOpen Access
    Nature Microbiology
    Volume: 10, P: 3069-3074

  • Determinants of Vibrio cholerae transmission are incompletely understood. Here, the authors use an infant mouse model to show that events in the intestine govern inter-animal transmission and that bacterial motility along with cholera toxin-driven diarrhea are critical for pathogen spread.

    • Ian W. Campbell
    • Ruchika Dehinwal
    • Matthew K. Waldor
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • Members of the DUF368-containing and DedA transmembrane protein families have conditional roles in undecaprenyl phosphate translocation in Gram-negative and Gram-positive bacteria and may have a widely conserved function in the biogenesis of microbial cell surface glycopolymers.

    • Brandon Sit
    • Veerasak Srisuknimit
    • Matthew K. Waldor
    ResearchOpen Access
    Nature
    Volume: 613, P: 721-728

  • Bacteria release outer membrane vesicles (OMVs) that play important roles in pathogenesis and intercellular interactions. Here, Roier et al. provide evidence supporting that phospholipid accumulation in the outer leaflet of the outer membrane participates in OMV formation in Gram-negative bacteria.

    • Sandro Roier
    • Franz G. Zingl
    • Stefan Schild
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-13