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Showing 1–4 of 4 results
Advanced filters: Author: Franziska Brüning Clear advanced filters

  • Protein ubiquitylation is often studied by proteomics but how data independent acquisition (DIA) may advance these studies remains to be explored. Here, the authors show that DIA improves ubiquitylation site identification and quantification, enabling them to characterize the circadian ubiquitinome in human cells.

    • Fynn M. Hansen
    • Maria C. Tanzer
    • Matthias Mann
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-13

  • Using large-scale single-nucleus transcriptomics, Nicin et al. report insights into human cardiac hypertrophy, caused by pressure overload, at single-cell resolution. The authors show that intercellular communication, particularly via the Eph receptor tyrosine kinase EPHB1, is impaired in human cardiomyopathy.

    • Luka Nicin
    • Sam Michael Schroeter
    • Stefanie Dimmeler
    ResearchOpen Access
    Nature Cardiovascular Research
    Volume: 1, P: 174-185